Antifungal behavior of silicon‐incorporated diamond‐like carbon by tuning surface hydrophobicity with plasma treatment
Antifungal behavior of silicon‐incorporated diamond‐like carbon by tuning surface hydrophobicity with plasma treatment
复制标题
通过等离子体处理调节表面疏水性，硅掺入类金刚石碳的抗真菌行为
DOI：
10.1111/ijac.14048
复制
发表时间：
2022
影响因子：
2.1
通讯作者：
Narayan, Roger J.
中科院分区：
文献类型：
--
作者：
Yang, Kai‐Hung;Riley, Parand;Rodenhausen, Keith B.;Skoog, Shelby A.;Stafslien, Shane J.;Vanderwal, Lyndsi;Narayan, Roger J.
硅掺杂类金刚石碳（Si - DLC）是一种含有硅原子与sp3 -和sp2 -杂化碳的非晶材料，由于其优异的机械性能、化学惰性、生物相容性和抗菌能力，是一种很有前途的生物医学应用生物材料。然而，等离子体处理的Si - DLC的抗真菌性能尚未得到系统的评估。在这项研究中，Si - DLC涂层通过化学气相沉积沉积，并进一步用氧或氟等离子体处理，使表面固定在不同的官能团和疏水性上。用原子力显微镜检测表面粗糙度，用拉曼光谱和X射线光电子能谱评估键合特性和表面成分。通过水接触角和zeta电位测量来研究润湿性和表面电荷。采用白色念珠菌多孔板筛选技术和结晶紫生物量定量进行抗真菌评价。结果表明，氧等离子体处理的Si - DLC具有亲水性，较低的负zeta电位和显著的抗真菌行为。这种材料可以潜在地应用于表面，以预防减少医院感染。
Silicon‐incorporated diamond‐like carbon (Si‐DLC), an amorphous material containing Si atoms with sp3‐ and sp2‐hybridized carbon, is a promising biomaterial for versatile biomedical applications due to its excellent mechanical properties, chemical inertness, biocompatibility, and antimicrobial capability. However, the antifungal properties of plasma‐treated Si‐DLC have not been systematically evaluated. In this study, Si‐DLC coatings were deposited by chemical vapor deposition and further treated with either oxygen or fluorine plasma to render the surface anchored with different functional groups and hydrophobicity. Surface roughness was probed with atomic force microscopy, whereas bonding character and surface composition were assessed using Raman and X‐ray photoelectron spectroscopy. Wettability and surface charge were investigated via water contact angle and zeta potential measurements. Antifungal assessment was performed using aCandida albicansmulti‐well plate screening technique and crystal violet biomass quantification. The results demonstrate that oxygen plasma–treated Si‐DLC exhibited hydrophilic properties, lower negative zeta potential, and significant antifungal behavior. This material can potentially be applied on surfaces for the prevention of reduced nosocomial infections.
登录
查看更多内容
通过等离子体聚合技术预防聚苯乙烯上念珠菌生物膜的形成
影响因子：
1.9
作者：
Gizem Kaleli;Elvan Hortaç;Hatice Ferda Özgüzar;M. Mutlu;H. Mirza;A. Basustaoglu;J. S. Göçmen
通讯作者：
J. S. Göçmen
影响因子：
--
作者：
Klauser, Frederik;Hermann, Martin;Lechleitner, Thomas
通讯作者：
Lechleitner, Thomas
影响因子：
2.1
作者：
Movahed, Saeid;Nguyen, Alexander K.;Narayan, Roger J.
通讯作者：
Narayan, Roger J.
影响因子：
2.4
作者：
Alanazi, A;Nojiri, C;Fukui, Y
通讯作者：
Fukui, Y
DOI：
10.1080/089419399272520
发表时间：
1999-05
期刊：
Journal of investigative surgery : the official journal of the Academy of Surgical Research
影响因子：
--
作者：
H. Tran;M. Puc;Charles W. Hewitt;D. Soll;S. Marra;Vincent A. Simonetti;J. Cilley;A. Delrossi
通讯作者：
H. Tran;M. Puc;Charles W. Hewitt;D. Soll;S. Marra;Vincent A. Simonetti;J. Cilley;A. Delrossi