Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries.
Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries.
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DOI：
10.1016/j.ajo.2016.06.023
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发表时间：
2016-09
影响因子：
4.2
通讯作者：
Yiu G
中科院分区：
文献类型：
--
作者：
Vuong VS;Moisseiev E;Cunefare D;Farsiu S;Moshiri A;Yiu G
通过比较增强深度成像光学相干断层扫描（edii - oct）对脉络膜-巩膜连接处不同后边界的定义，评估人工测量脉络膜厚度的可靠性。两名评分者采用不同的后边界(1)脉络膜血管腔外边界，2)脉络膜间质外边界，3)巩膜内边界，用分割软件对脉络膜-巩膜交界处进行标记，分别测量血管脉络膜厚度（VCT），脉络膜间质厚度（SCT），脉络膜总厚度（TCT）。测量间隔为0.5 mm，从1.5 mm鼻到1.5 mm颞到中央凹，平均连续测量黄斑中心3mm。通过比较分类内相关系数（ICC）和信度系数（CR）来评估分类间和分类间的信度。脉络膜厚度测量值随后验边界的不同有显著差异（P = <0.001）。即使在脉络膜-巩膜连接处能见度<75%的眼睛中，SCT的积分icc（0.959 - 0.980）高于TCT（0.928 - 0.963）和VCT（0.750 - 0.869）。SCT的综合评分（41.40 - 62.31）低于TCT（61.13 - 74.24）或VCT（72.44 - 115.11）。ICCs和CRs对平均VCT、SCT或TCT测量结果的可靠性高于单个位置。整合者ICCs和CRs与整合者值相当。当测量到脉络膜间质（SCT）的边界时，脉络膜厚度测量比血管腔（VCT）或巩膜（TCT）更具有可重复性。
To assess the reliability of manual choroidal thickness measurements by comparing different posterior boundary definitions of the choroidal-scleral junction on enhanced depth imaging optical coherence tomography (EDI-OCT). Reliability analysis Two graders marked the choroidal-scleral junction with segmentation software using different posterior boundaries: 1) the outer border of the choroidal vessel lumen, 2) the outer border of the choroid stroma, and 3) the inner border of the sclera, to measure the vascular choroidal thickness (VCT), stromal choroidal thickness (SCT), and total choroidal thickness (TCT), respectively. Measurements were taken at 0.5 mm intervals from 1.5 mm nasal to 1.5 mm temporal to the fovea, and averaged continuously across the central 3 mm of the macula. Intraclass correlation coefficient (ICC) and coefficient of reliability (CR) were compared to assess intergrader and intragrader reliability. Choroidal thickness measurements varied significantly with different posterior boundaries (P = <0.001 for all). Intergrader ICCs were greater for SCT (0.959 – 0.980) than TCT (0.928 – 0.963) and VCT (0.750 – 0.869), even in eyes where choroidal-scleral junction visibility was <75%. Intergrader CRs were lower for SCT (41.40 – 62.31) than TCT (61.13 – 74.24) or VCT (72.44 – 115.11). ICCs and CRs showed greater reliability for averaged VCT, SCT, or TCT measurements, than at individual locations. Intragrader ICCs and CRs were comparable to intergrader values. Choroidal thickness measurements are more reproducible when measured to the border of the choroid stroma (SCT) than the vascular lumen (VCT) or sclera (TCT).
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影响因子：
13.7
作者：
Chung, Song Ee;Kang, Se Woong;Kim, Yun Taek
通讯作者：
Kim, Yun Taek
影响因子：
2
作者：
Chen, Wei;Song, Hui;Chu, Yanhua
通讯作者：
Chu, Yanhua
影响因子：
4.4
作者：
Lin, Phoebe;Mettu, Priyatham S.;Mruthyunjaya, Prithvi
通讯作者：
Mruthyunjaya, Prithvi
影响因子：
8.1
作者：
Adhi, Mehreen;Brewer, Erika;Waheed, Nadia K.;Duker, Jay S.
通讯作者：
Duker, Jay S.
DOI：
10.2147/opth.s53989
发表时间：
2014
期刊：
Clinical ophthalmology (Auckland, N.Z.)
影响因子：
--
作者：
Falcão MS;Gonçalves NM;Freitas-Costa P;Beato JB;Rocha-Sousa A;Carneiro A;Brandão EM;Falcão-Reis FM
通讯作者：
Falcão-Reis FM