Mechanisms of vagal plasticity influencing feeding behavior.

Mechanisms of vagal plasticity influencing feeding behavior.
复制标题

DOI:
10.1016/j.brainres.2018.03.030
复制
发表时间:
2018-08-15
期刊:
影响因子:
2.9
通讯作者:
Xu C
Xu C
中科院分区:
医学3区
文献类型:
--
作者:
de Lartigue G;Xu C

文献摘要

参考文献

被引文献

相似文献

迷走神经的感觉神经元接收许多不同的外周信号,这些信号可以在一天中迅速而频繁地变化。这些神经元向大脑传递大量细微差别信息的能力需要神经元的适应性。在这篇综述中,我们讨论了迷走神经传入神经元神经可塑性的证据,它是一种将细微差别的信息传递到大脑的机制,对控制摄食行为至关重要。我们提供的证据表明,突触可塑性、膜电导的变化和神经肽规格是允许灵活反应代谢线索的机制,这些代谢线索可能会被长期摄入高能量饮食所破坏。
Sensory neurons of the vagus nerve receive many different peripheral signals that can change rapidly and frequently throughout the day. The ability of these neurons to convey the vast array of nuanced information to the brain requires neuronal adaptability. In this review we discuss evidence for neural plasticity in vagal afferent neurons as a mechanism for conveying nuanced information to the brain important for the control of feeding behavior. We provide evidence that synaptic plasticity, changes in membrane conductance, and neuropeptide specification are mechanisms that allow flexibility in response to metabolic cues that can be disrupted by chronic intake of energy dense diets.
DOI: 10.1126/science.1234152
发表时间: 2013-04-26
期刊: SCIENCE
影响因子: 56.9
作者:
Dulcis, Davide;Jamshidi, Pouya;Spitzer, Nicholas C.
通讯作者: Spitzer, Nicholas C.
DOI: 10.1038/ijo.2012.45
发表时间: 2013-03-01
影响因子: 4.9
作者:
Duca, F. A.;Swartz, T. D.;Covasa, M.
通讯作者: Covasa, M.
DOI: 10.1111/j.1748-1716.1971.tb04960.x
发表时间: 1971-01-01
期刊: ACTA PHYSIOLOGICA SCANDINAVICA
影响因子: --
作者:
GIACOBINI, E;NORE, B
通讯作者: NORE, B
迷走神经的肥胖关键。
DOI: 10.1016/j.molmet.2014.09.009
发表时间: 2014-12
影响因子: 8.1
作者:
de Lartigue G;Ronveaux CC;Raybould HE
通讯作者: Raybould HE
DOI: 10.1126/science.1209236
发表时间: 2011-11-04
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Ho VM;Lee JA;Martin KC
通讯作者: Martin KC