REAL-TIME ASSESSMENT OF MICROWAVE ABLATION EFFICACY BY NIR SPECTROSCOPIC TECHNIQUE
REAL-TIME ASSESSMENT OF MICROWAVE ABLATION EFFICACY BY NIR SPECTROSCOPIC TECHNIQUE
复制标题
通过近红外光谱技术实时评估微波消融效果
DOI：
10.1142/s1793545813500533
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发表时间：
2014-01
影响因子：
2.5
通讯作者：
Wu Jiali
中科院分区：
文献类型：
--
作者：
Zhao Jinzhe;Qian Zhiyu;Liu Jia;Xu Ya;Wu Jiali
微波消融（MWA）状态的真实的实时监测是评估疗效的关键。近红外光谱作为一种新的实时评估方法，被用来评估消融效果。在体外猪肝上进行MWA实验。本实验室研制了一套用于生物组织凝固区690 nm处约化散射系数的光学测量系统。值得注意的是，随着肝组织被消融，肝组织的$\mu_{s}^g '}$增加，与凝血状态明显相关。正常组织和凝固组织的$\mu_{s}^m '}$分别为3-5和17-19 cm-1。$\mu_{s}^λ '}$的连续变化表明，光学参数本质上反映了热损伤的程度，可以作为一个效能评价因子。与温度相比，光学参数具有更高的灵敏度和准确性，有望用于实时疗效评估。
Microwave ablation (MWA) status monitoring in real time plays a key role in assessment of therapeutic effectiveness. As a novel real-time assessment method, near infrared spectroscopy (NIRs) was used to evaluate the ablation efficacy. MWA experiments were carried out on in vitro porcine livers. An optical measurement system for biological tissue is developed by our lab to monitor reduced scattering coefficient $(\mu_{s}^{'})$ at 690 nm of the coagulation zones. It is noted that $\mu_{s}^{'}$ of liver tissue, which increases as the liver tissue being ablated, is clearly related with the coagulation status. $\mu_{s}^{'}$ of normal tissue and coagulated tissue is 3–5 and 17–19 cm-1, respectively. Continuous changes of $\mu_{s}^{'}$ demonstrate that optical parameter can be used as an efficacy evaluation factor because it essentially indicates the degree of thermal damage. Compared with temperature, optical parameter is more sensitive and accurate, which is promising for real-time therapeutic efficacy assessm...
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影响因子：
3.1
作者：
Qiujie Shao;Z. Han;Xiao-xia Ni;W. Shi;Yuan-yuan Sun;Hong Liu;L. Xin;L. Ping
通讯作者：
Qiujie Shao;Z. Han;Xiao-xia Ni;W. Shi;Yuan-yuan Sun;Hong Liu;L. Xin;L. Ping
DOI：
10.1117/12.364421
发表时间：
1999-09
期刊：
--
影响因子：
--
作者：
D. Zhu;Qingming Luo;Jiangsheng Yu;Shaoqun Zeng;R. Yu
通讯作者：
D. Zhu;Qingming Luo;Jiangsheng Yu;Shaoqun Zeng;R. Yu
影响因子：
3.1
作者：
Liu, Fang-Yi;Yu, Xiao-Ling;Yu, Jie
通讯作者：
Yu, Jie
影响因子：
3.5
作者：
Buttemere, CR;Chari, RS;Lin, WC
通讯作者：
Lin, WC
影响因子：
1.9
作者：
Jie-ru Xie;Z. Qian;Tian-ming Yang;Weitao Li;Guangxia Hu
通讯作者：
Jie-ru Xie;Z. Qian;Tian-ming Yang;Weitao Li;Guangxia Hu