The First Report of Cerebral Nocardiosis Caused by Nocardia terpenica Together With Exiguobacterium profundum Bacteremia

The First Report of Cerebral Nocardiosis Caused by Nocardia terpenica Together With Exiguobacterium profundum Bacteremia
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萜类诺卡菌与深微小杆菌菌血症所致脑诺卡菌病首例报道

DOI:
10.5812/jjm.69604
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发表时间:
2018-10
期刊:
Jundishapur J Microbiol
影响因子:
--
通讯作者:
Lingbing Zeng
Lingbing Zeng
中科院分区:
其他
文献类型:
--
作者:
Niya Hu;Wei Zou;Qingming Cai;Yanling Liu;Kaisen Chen;Ming Li;Yongming Tan;Qing Zhu;Lingbing Zeng

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前言:随着抗生素的广泛使用和免疫功能低下患者数量的不断增加,许多罕见的细菌感染也呈上升趋势。近年来,仅有少数患者出现中枢神经系统诺卡氏菌病和外阴杆菌菌血症。然而,中枢神经系统诺卡氏菌病合并外阴杆菌菌血症的病例尚未见报道。病例介绍:患者因中枢神经系统感染症状住进三级医院。脑脊液和血液均送往培养。通过16S rRNA测序,从脑脊液和血液中分离到病原菌,最终鉴定为诺卡氏菌和外阴杆菌。结论:这是首例在无中枢神经系统脓肿形成的患者中报告的中枢神经系统肺炎诺卡菌感染病例。此外,这名患者还患有复杂的感染,涉及深埃希格杆菌菌血症。
Introduction: With the widespread use of antibiotics and increasing number of immunocompromised patients, many rare bacterial infections have become increasing. Recently, only a few cases showed central nervous system (CNS) nocardiosis and Exiguobacterium bacteremia. However, the case that CNS nocardiosis together with Exiguobacterium bacteremia has never been reported. Case Presentation: The patient was admitted to a tertiary hospital with CNS infection symptoms. Cerebrospinal fluid and blood were both sent to culture. Pathogens were both isolated from cerebrospinal fluid and blood, following 16s rRNA sequencing, which were finally identified as Nocardia and Exiguobacterium species. Conclusions: It is the first reported case of CNS Nocardia terpenica infection in a patient without abscess formation in the CNS. Additionally, this patient also had a complex infection involving Exiguobacterium profundum bacteremia.
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