The vicious cycle of itch and anxiety.

The vicious cycle of itch and anxiety.
复制标题

DOI:
10.1016/j.neubiorev.2018.01.009
复制
发表时间:
2018-04
影响因子:
8.2
通讯作者:
Akiyama T
Akiyama T
中科院分区:
医学1区
文献类型:
--
作者:
Sanders KM;Akiyama T

文献摘要

参考文献

被引文献

相似文献

慢性瘙痒与压力增加、焦虑和其他情绪障碍有关。反过来,压力和焦虑会加剧瘙痒,导致恶性循环,影响患者的行为(抓挠),并影响疾病预后和生活质量。这种循环在不同病因的慢性瘙痒症中持续存在,甚至在某种程度上在健康个体中持续存在,这表明瘙痒处理的最终共同途径(中枢神经系统)在瘙痒和焦虑之间的关系中起着重要作用。减少焦虑的药物和非药物治疗已经显示出有希望的止痒效果。需要进一步的研究来建立瘙痒-焦虑循环的特定中枢机制,并提供新的治疗靶点。
Chronic itch is associated with increased stress, anxiety, and other mood disorders. In turn, stress and anxiety exacerbate itch, leading to a vicious cycle that affects patient behavior (scratching) and worsens disease prognosis and quality of life. This cycle persists across chronic itch conditions of different etiologies and even to some extent in healthy individuals, suggesting that the final common pathway for itch processing (the central nervous system) plays a major role in the relationship between itch and anxiety. Pharmacological and nonpharmacological treatments that reduce anxiety have shown promising anti-itch effects. Further research is needed to establish specific central mechanisms of the itch-anxiety cycle and provide new targets for treatment.
DOI: 10.1038/sj.npp.1301435
发表时间: 2008-02-01
影响因子: 7.6
作者:
Amano, Hiroo;Negishi, Izumi;Ishikawa, Osamu
通讯作者: Ishikawa, Osamu
DOI: 10.1007/s40257-014-0075-7
发表时间: 2014-08-01
影响因子: 7.3
作者:
Altunay, Ilknur Kivanc;Atis, Guldehan;Kucukunal, Asli
通讯作者: Kucukunal, Asli
DOI: 10.1111/dth.12459
发表时间: 2017-03-01
影响因子: 3.6
作者:
Atis, Guldehan;Kaya, Basak Bilir
通讯作者: Kaya, Basak Bilir
DOI: 10.1016/j.aller.2012.05.007
发表时间: 2013-07-01
影响因子: 1.8
作者:
Comert, S.;Celebioglu, E.;Kalyoncu, A. F.
通讯作者: Kalyoncu, A. F.
DOI: 10.1371/journal.pone.0091727
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者:
Bartels DJ;van Laarhoven AI;Haverkamp EA;Wilder-Smith OH;Donders AR;van Middendorp H;van de Kerkhof PC;Evers AW
通讯作者: Evers AW