The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination-An Analysis of Serological Response and Side Effects.
The Gender Impact Assessment among Healthcare Workers in the SARS-CoV-2 Vaccination-An Analysis of Serological Response and Side Effects.
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DOI：
10.3390/vaccines9050522
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发表时间：
2021-05-18
期刊：
影响因子：
7.8
通讯作者：
Tomaiuolo R
中科院分区：
文献类型：
--
作者：
Di Resta C;Ferrari D;Viganò M;Moro M;Sabetta E;Minerva M;Ambrosio A;Locatelli M;Tomaiuolo R
医护人员被认为是SARS-CoV-2暴露和传播的高风险人群，因此被认为是COVID-19疫苗接种运动策略的优先群体。然而，必须假设免疫反应受到许多因素的影响，包括性和性别。对这些因素的分析是对人群进行分层和确定疫苗接种策略的影响因素。因此，对参加意大利SARS-CoV-2疫苗接种活动的大量医护人员进行了研究，以使用性别影响评估方法确定性别和性别对疫苗接种覆盖率的影响。本研究显示，不同年龄和性别组的抗体滴度存在显著差异，年龄较大组的抗体滴度有明显下降趋势。总体而言，女性的血清学值显著较高;女性报告的副作用比男性更常见。因此，分类数据指出了性别因素的评估在COVID-19疫苗接种策略中的重要性。在此生物医学和社会的基础上，提供建议，以改善SARS-CoV-2疫苗接种运动的医疗保健专业人员。不过，它们可以适用于其他类别和背景。
Healthcare professionals are considered to be at high risk of exposure and spread of SARS-CoV-2, and have therefore been considered a priority group in COVID-19 vaccination campaign strategies. However, it must be assumed that the immune response is influenced by numerous factors, including sex and gender. The analysis of these factors is an impact element for stratifying the population and targeting the vaccination strategy. Therefore, a large cohort of healthcare workers participating in the Italian vaccination campaign against SARS-CoV-2 has been studied to establish the impact of sex and gender on vaccination coverage using the Gender Impact Assessment approach. This study shows a significant difference in the antibody titers among different age and sex groups, with a clear decreasing trend in antibody titers in the older age groups. Overall, the serological values were significantly higher in females; the reported side effects are more frequent in females than in males. Therefore, disaggregated data point out how the evaluation of gender factors could be essential in COVID-19 vaccination strategies. On this biomedical and social basis, suggestions are provided to improve the SARS-CoV-2 vaccination campaign in healthcare professionals. Still, they could be adapted to other categories and contexts.
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影响因子：
6.1
作者：
GIGLIO, T;IMRO, MA;COSTANTINI, S
通讯作者：
COSTANTINI, S
DOI：
10.3390/life11030249
发表时间：
2021-03-17
期刊：
Life (Basel, Switzerland)
影响因子：
--
作者：
Mathioudakis AG;Ghrew M;Ustianowski A;Ahmad S;Borrow R;Papavasileiou LP;Petrakis D;Bakerly ND
通讯作者：
Bakerly ND
影响因子：
7.8
作者：
Giefing-Kröll C;Berger P;Lepperdinger G;Grubeck-Loebenstein B
通讯作者：
Grubeck-Loebenstein B
影响因子：
4.5
作者：
Davies, Sara E.;Bennett, Belinda
通讯作者：
Bennett, Belinda
DOI：
10.1007/978-3-642-02155-8_3
发表时间：
2010-01-01
期刊：
SEX HORMONES AND IMMUNITY TO INFECTION
影响因子：
--
作者：
Kovats, Susan;Carreras, Esther;Agrawal, Hemant
通讯作者：
Agrawal, Hemant