Host-microbe circadian dynamics: Finding a rhythm and hitting a groove in scientific inquiry.

Host-microbe circadian dynamics: Finding a rhythm and hitting a groove in scientific inquiry.
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DOI:
10.1016/j.chom.2022.03.008
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发表时间:
2022-04-13
影响因子:
30.3
通讯作者:
Leone, Vanessa A.
Leone, Vanessa A.
中科院分区:
医学1区
文献类型:
--
作者:
Frazier, Katya;Leone, Vanessa A.

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肠道微生物是生物体水平昼夜节律的中介者,对环境提示做出反应并进行传递。肠道微生物也表现出节律,但它们对健康微生物群的贡献尚不清楚。我们提出了识别与健康相关的宿主-微生物昼夜节律动力学的途径,并概述了一系列需要进一步探索的前瞻性问题。
Gut microbes are mediators of organismal-level circadian rhythms, responding to and transducing environmental cues. Gut microbes also exhibit rhythms, yet their contribution to a healthy microbiome remains unclear. We present our path to identifying host-microbe circadian dynamics related to health and outline a series of forward-thinking questions requiring further exploration.
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