Bayesian Factor Analysis for Inference on Interactions.
Bayesian Factor Analysis for Inference on Interactions.
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DOI:
10.1080/01621459.2020.1745813
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发表时间:
2021
影响因子:
3.7
通讯作者:
Dunson DB
中科院分区:
文献类型:
--
作者:
Ferrari F;Dunson DB
This article is motivated by the problem of inference on interactions among chemical exposures impacting human health outcomes. Chemicals often co-occur in the environment or in synthetic mixtures and as a result exposure levels can be highly correlated. We propose a latent factor joint model, which includes shared factors in both the predictor and response components while assuming conditional independence. By including a quadratic regression in the latent variables in the response component, we induce flexible dimension reduction in characterizing main effects and interactions. We propose a Bayesian approach to inference under this Factor analysis for INteractions (FIN) framework. Through appropriate modifications of the factor modeling structure, FIN can accommodate higher order interactions. We evaluate the performance using a simulation study and data from the National Health and Nutrition Examination Survey (NHANES). Code is available on GitHub.
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DOI:
10.1038/nrendo.2016.186
发表时间:
2017-03
期刊:
Nature reviews. Endocrinology
影响因子:
--
作者:
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通讯作者:
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DOI:
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发表时间:
2009-06
期刊:
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影响因子:
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作者:
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影响因子:
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通讯作者:
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DOI:
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发表时间:
1996-03-01
影响因子:
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作者:
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影响因子:
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