The Seminiferous Epithelial Cycle of Spermatogenesis: Role of Non-receptor Tyrosine Kinases.
The Seminiferous Epithelial Cycle of Spermatogenesis: Role of Non-receptor Tyrosine Kinases.
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精子发生的生精上皮周期:非受体酪氨酸激酶的作用。
DOI:
10.1007/978-3-030-77779-1_1
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发表时间:
2021
影响因子:
--
通讯作者:
Ni Ya
中科院分区:
文献类型:
--
作者:
Xiao Xiang;Zheng Dongwang;Liang Fei;Ying Shibo;Sun Peibei;Yu Jianmin;Ni Ya
Non-receptor tyrosine kinases (NRTKs) are implicated in various biological processes including cell proliferation, differentiation, survival, and apoptosis, as well as cell adhesion and movement. NRTKs are expressed in all mammals and in different cell types, with extraordinarily high expression in the testis. Their association with the plasma membrane and dynamic subcellular localization are crucial parameters in their activation and function. Many NRTKs are found in endosomal protein trafficking pathways, which suggests a novel mechanism to regulate the timely junction restructuring in the mammalian testis to facilitate spermiation and germ cell transport across the seminiferous epithelium.
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DOI:
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