Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision.
Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision.
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DOI：
10.3390/jof3040057
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发表时间：
2017-10-18
期刊：
影响因子：
--
通讯作者：
Denning DW
中科院分区：
文献类型：
--
作者：
Bongomin F;Gago S;Oladele RO;Denning DW
真菌疾病造成150多万人死亡，影响10亿多人。然而，它们仍然是公共卫生当局忽视的话题，尽管大多数真菌疾病的死亡是可以避免的。严重的真菌感染是其他健康问题的结果，包括哮喘、艾滋病、癌症、器官移植和皮质类固醇治疗。早期准确的诊断允许及时的抗真菌治疗;然而，这通常是延迟或不可用，导致死亡，严重的慢性疾病或失明。最近的全球估计发现了3，000，000例慢性肺曲霉病，约223，100例隐球菌脑膜炎并发艾滋病毒/艾滋病，约700，000例侵袭性念珠菌病，约500，000例肺囊虫肺炎，约250，000例侵袭性曲霉病，约100，000例播散性组织胞浆菌病，10多例，每年发生约1，000，000例真菌性哮喘和约1，000，000例真菌性角膜炎。自2013年以来，领先的国际真菌教育（LIFE）门户网站促进了对超过57亿人（占世界人口的80%）的严重真菌感染负担的估计。这些研究表明，不同国家之间、同一国家的不同地区之间以及不同风险人群之间的全球负担存在差异。在这里，我们询问这些真菌感染负担估计的准确性在43篇已发表的论文中的生命倡议。
Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are still a neglected topic by public health authorities even though most deaths from fungal diseases are avoidable. Serious fungal infections occur as a consequence of other health problems including asthma, AIDS, cancer, organ transplantation and corticosteroid therapies. Early accurate diagnosis allows prompt antifungal therapy; however this is often delayed or unavailable leading to death, serious chronic illness or blindness. Recent global estimates have found 3,000,000 cases of chronic pulmonary aspergillosis, ~223,100 cases of cryptococcal meningitis complicating HIV/AIDS, ~700,000 cases of invasive candidiasis, ~500,000 cases of Pneumocystis jirovecii pneumonia, ~250,000 cases of invasive aspergillosis, ~100,000 cases of disseminated histoplasmosis, over 10,000,000 cases of fungal asthma and ~1,000,000 cases of fungal keratitis occur annually. Since 2013, the Leading International Fungal Education (LIFE) portal has facilitated the estimation of the burden of serious fungal infections country by country for over 5.7 billion people (>80% of the world’s population). These studies have shown differences in the global burden between countries, within regions of the same country and between at risk populations. Here we interrogate the accuracy of these fungal infection burden estimates in the 43 published papers within the LIFE initiative.
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影响因子：
2
作者：
Cao J;Yang Y;Yang W;Wu R;Xiao X;Yuan J;Xing Y;Tan X
通讯作者：
Tan X
影响因子：
4.9
作者：
Badiane, Aida S.;Ndiaye, Daouda;Denning, David W.
通讯作者：
Denning, David W.
影响因子：
4.3
作者：
Al-Mobeireek, AF;El-Rab, MOG;Joharjy, I
通讯作者：
Joharjy, I
影响因子：
0.8
作者：
Ayanlowo, Olusola;Akinkugbe, Ayesha;Balogun, Mobolanle
通讯作者：
Balogun, Mobolanle
对囊性纤维化中曲霉菌病不同表现的多国评估。
影响因子：
3.7
作者：
Armstead J;Morris J;Denning DW
通讯作者：
Denning DW