Ultra-high field magnetic resonance imaging of the basal ganglia and related structures.
Ultra-high field magnetic resonance imaging of the basal ganglia and related structures.
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DOI：
10.3389/fnhum.2014.00876
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发表时间：
2014
影响因子：
2.9
通讯作者：
Ter Haar Romenij BM
中科院分区：
文献类型：
--
作者：
Plantinga BR;Temel Y;Roebroeck A;Uludağ K;Ivanov D;Kuijf ML;Ter Haar Romenij BM
脑深部电刺激是一种治疗帕金森氏病和其他相关疾病的方法，涉及在位于深部的基底神经节或丘脑结构中手术放置电极。良好的临床结果需要准确的靶向。然而，由于常规临床MR图像上目标结构的可见性有限，结构的直接靶向可能具有挑战性。具有超高磁场（7T或更高）的非临床MR扫描仪有可能提高这些图像的质量。本技术报告概述了目前借助超高场MRI可视化脑深部电刺激目标及其相关结构的可能性。审查的研究表明，提高分辨率，对比度和信噪比在超高场。对磁化率敏感的序列（如T2*）和磁敏感加权成像及其图通常显示了靶结构的最佳可视化，包括丘脑底核和黑质之间的分离、苍白球内的内侧苍白层和不完全苍白层以及丘脑的亚结构，包括腹侧中间核（Vim）。这表明，小的深部脑刺激目标的可见性、识别、甚至细分受益于增加的场强。尽管超高场MR成像与几何失真的增加的风险相关联，但是已经表明，这些失真可以被避免或校正到影响有限的程度。人类超高场MR扫描仪的可用性似乎为帕金森病和相关疾病患者的深部脑刺激提供了更准确的靶向机会。
Deep brain stimulation is a treatment for Parkinson's disease and other related disorders, involving the surgical placement of electrodes in the deeply situated basal ganglia or thalamic structures. Good clinical outcome requires accurate targeting. However, due to limited visibility of the target structures on routine clinical MR images, direct targeting of structures can be challenging. Non-clinical MR scanners with ultra-high magnetic field (7T or higher) have the potential to improve the quality of these images. This technology report provides an overview of the current possibilities of visualizing deep brain stimulation targets and their related structures with the aid of ultra-high field MRI. Reviewed studies showed improved resolution, contrast- and signal-to-noise ratios at ultra-high field. Sequences sensitive to magnetic susceptibility such as T2* and susceptibility weighted imaging and their maps in general showed the best visualization of target structures, including a separation between the subthalamic nucleus and the substantia nigra, the lamina pallidi medialis and lamina pallidi incompleta within the globus pallidus and substructures of the thalamus, including the ventral intermediate nucleus (Vim). This shows that the visibility, identification, and even subdivision of the small deep brain stimulation targets benefit from increased field strength. Although ultra-high field MR imaging is associated with increased risk of geometrical distortions, it has been shown that these distortions can be avoided or corrected to the extent where the effects are limited. The availability of ultra-high field MR scanners for humans seems to provide opportunities for a more accurate targeting for deep brain stimulation in patients with Parkinson's disease and related disorders.
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使用 7 特斯拉磁共振成像直接可视化帕金森病的深部脑刺激目标。
影响因子：
4.1
作者：
Cho ZH;Min HK;Oh SH;Han JY;Park CW;Chi JG;Kim YB;Paek SH;Lozano AM;Lee KH
通讯作者：
Lee KH
影响因子：
2.9
作者：
Deistung A;Schäfer A;Schweser F;Biedermann U;Güllmar D;Trampel R;Turner R;Reichenbach JR
通讯作者：
Reichenbach JR
影响因子：
1.3
作者：
Bourekas, EC;Christofoidis, GA;Robitaille, PML
通讯作者：
Robitaille, PML
影响因子：
3.5
作者：
Bender, B.;Maenz, C.;Klose, U.
通讯作者：
Klose, U.
DOI：
10.1016/j.jmr.2010.06.006
发表时间：
2010-09
期刊：
Journal of magnetic resonance (San Diego, Calif. : 1997)
影响因子：
--
作者：
Deelchand DK;Van de Moortele PF;Adriany G;Iltis I;Andersen P;Strupp JP;Vaughan JT;Uğurbil K;Henry PG
通讯作者：
Henry PG