A heartfelt response: Oxytocin effects on response to social stress in men and women.
A heartfelt response: Oxytocin effects on response to social stress in men and women.
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DOI：
10.1016/j.biopsycho.2012.02.010
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发表时间：
2012-04
影响因子：
2.6
通讯作者：
Adler, Gail K.
中科院分区：
文献类型：
--
作者：
Kubzansky, Laura D.;Mendes, Wendy Berry;Appleton, Allison A.;Block, Jason;Adler, Gail K.
动物研究表明，催产素参与社会行为、压力调节和积极的生理适应。这项研究考察了催产素是否增强了对社会压力的适应性反应，并比较了男性和女性之间的影响。假说通过安慰剂对照的双盲实验进行了检验。诱发了社会压力。评估心血管反应性、情感和行为的变化。与安慰剂相比，服用催产素的参与者对社会压力的反应是以一种以心血管反应良性模式为特征的挑战导向。性别差异出现了。服用催产素的男性报告的负面情绪较少，迷走神经反弹更大，而服用催产素的女性报告的愤怒更多，在社交压力下的数学表现更好。研究结果表明，在社交压力下，催产素可以刺激一种以方法为导向的心血管状况，这表明催产素可能通过哪些机制改善身体健康。然而，在考虑将催产素作为治疗或统一促进健康的药物之前，需要更好地了解可能存在的性别差异的影响。
Animal research indicates that oxytocin is involved in social behavior, stress regulation, and positive physiologic adaptation. This study examines whether oxytocin enhances adaptive responses to social stress and compares effects between men and women. Hypotheses were tested with a placebo-controlled, double-blind experiment. Social stress was induced. Changes in cardiovascular reactivity, affect, and behavior were assessed. Participants given oxytocin, relative to placebo, responded to social stress with a challenge orientation characterized by a benign pattern of cardiovascular reactivity. Gender differences emerged. Men given oxytocin reported less negative affect and had greater vagal rebound, while women given oxytocin reported more anger and had better math performance following social stress. Findings indicate oxytocin stimulates an approach-oriented cardiovascular profile during social stress, suggesting mechanisms by which oxytocin might improve physical health. However, before considering oxytocin as therapeutic or uniformly enhancing health, greater understanding of possible gender differences in effects is needed.
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影响因子：
3.7
作者：
CACIOPPO, JT;UCHINO, BN;BERNTSON, GG
通讯作者：
BERNTSON, GG
影响因子：
2.9
作者：
Heinrichs, M;Meinlschmidt, G;Hellhammer, DH
通讯作者：
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影响因子：
3.3
作者：
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通讯作者：
Berntson, GG
DOI：
10.1017/cbo9780511546396.008
发表时间：
2007-01-01
期刊：
HANDBOOK OF PSYCHOPHYSIOLOGY, 3RD EDITION
影响因子：
--
作者：
Berntson, Gary G.;Quigley, Karen S.;Lozano, Dave
通讯作者：
Lozano, Dave
影响因子：
3.3
作者：
Cyranowski JM;Hofkens TL;Frank E;Seltman H;Cai HM;Amico JA
通讯作者：
Amico JA