A bird's eye view of neural circuit formation.

A bird's eye view of neural circuit formation.
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DOI:
10.1016/j.conb.2010.08.001
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发表时间:
2011-02
影响因子:
5.7
通讯作者:
Gardner TJ
Gardner TJ
中科院分区:
医学2区
文献类型:
--
作者:
Olveczky BP;Gardner TJ

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复杂习得行为(例如人类言语)背后的神经回路是在遗传限制和环境影响下发展起来的。人们对这种电路形成的规则和机制知之甚少。我们认为,鸣禽的离散且经过充分研究的神经通路构成了复杂且自然学习的行为,为解决这些问题提供了一个强大的模型。我们简要回顾了当前关于歌曲电路在学习过程中如何发展的知识,并讨论了鉴于最新的技术进步推进该领域的新可能性。
Neural circuits underlying complex learned behaviors, such as speech in humans, develop under genetic constraints and in response to environmental influences. Little is known about the rules and mechanisms through which such circuits form. We argue that songbirds, with their discrete and well studied neural pathways underlying a complex and naturally learned behavior, provide a powerful model for addressing these questions. We briefly review current knowledge of how the song circuit develops during learning and discuss new possibilities for advancing the field given recent technological advances.
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