Understanding obesity and endometrial cancer risk: opportunities for prevention.
Understanding obesity and endometrial cancer risk: opportunities for prevention.
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DOI:
10.1016/j.ajog.2011.05.042
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发表时间:
2011-12
影响因子:
9.8
通讯作者:
Lu KH
中科院分区:
文献类型:
--
作者:
Schmandt RE;Iglesias DA;Co NN;Lu KH
Worldwide, obesity has become a major public health crisis. Overweight and obesity not only increase the risk of cardiovascular disease and type-2 diabetes, but also are now known risk factors for a variety of cancer types. Among all cancers, increasing body mass index is most strongly associated with endometrial cancer incidence and mortality. The molecular mechanisms underlying how adipose tissue and obesity contribute to the pathogenesis of endometrial cancer are becoming better understood and have revealed a number of rational strategies, both behavioral and pharmaceutical, for the prevention of both primary and recurrent disease.
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