Neuronal odor coding in the larval sensory cone of Anopheles coluzzii: Complex responses from a simple system.
Neuronal odor coding in the larval sensory cone of Anopheles coluzzii: Complex responses from a simple system.
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DOI：
10.1016/j.celrep.2021.109555
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发表时间：
2021-08-17
期刊：
影响因子：
8.8
通讯作者：
Zwiebel LJ
中科院分区：
文献类型：
--
作者：
Sun H;Liu F;Baker AP;Honegger HW;Raiser G;Zwiebel LJ
按蚊是疟疾的唯一传播媒介。虽然成年雌性直接负责疾病传播，因此已被广泛研究，但成虫前期幼虫的存活是至关重要的。蚊子幼虫利用一系列化学感觉和其他线索来导航它们的水生栖息地，以躲避捕食者和寻找食物。在这里，我们研究了幼虫的嗅觉反应，其中外围组件与触角感觉锥有关。库鲁兹按蚊的幼虫行为和对挥发性刺激的感觉锥反应表明，感觉锥对酒精、噻唑和杂环化合物特别敏感，这些反应可以分配给具有不同轮廓的感觉锥神经元离散组。这些研究表明，按蚊幼虫通过高度复杂的嗅觉系统在其水生栖息地上方活跃地品尝挥发性气味，该系统对广泛的具有显著行为相关性的化合物很敏感。Sun等人。研究库鲁兹按蚊幼虫对挥发性刺激的感觉锥和行为反应。他们发现，疟疾蚊子幼虫通过高度复杂的嗅觉系统在其水生栖息地上方积极地品尝挥发性气味，该系统对广泛的与行为相关的化合物很敏感。
Anopheles mosquitoes are the sole vectors of malaria. Although adult females are directly responsible for disease transmission and accordingly have been extensively studied, the survival of pre-adult larval stages is vital. Mosquito larvae utilize a spectrum of chemosensory and other cues to navigate their aquatic habitats to avoid predators and search for food. Here we examine larval olfactory responses, in which the peripheral components are associated with the antennal sensory cone. Larval behavior and sensory cone responses to volatile stimuli in Anopheles coluzzii demonstrate the sensory cone is particularly tuned to alcohols, thiazoles, and heterocyclics, and these responses can be assigned to discrete groups of sensory cone neurons with distinctive profiles. These studies reveal that the anopheline larvae actively sample volatile odors above their aquatic habitats via a highly sophisticated olfactory system that is sensitive to a broad range of compounds with significant behavioral relevance. Sun et al. investigate larval sensory cone and behavioral responses to volatile stimuli in Anopheles coluzzii. They find that malaria mosquito larvae actively sample volatile odors above their aquatic habitats via a highly sophisticated olfactory system that is sensitive to a broad range of compounds with significant behavioral relevance.
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影响因子：
3.3
作者：
Fillinger, U;Sonye, G;Becker, N
通讯作者：
Becker, N
影响因子：
2.6
作者：
Bohbot, J.;Pitts, R. J.;Zwiebel, L. J.
通讯作者：
Zwiebel, L. J.
影响因子：
2.2
作者：
DENOTTER, CJ;BEHAN, M;MAES, FW
通讯作者：
MAES, FW
DOI：
10.1073/pnas.260499897
发表时间：
2000-12-19
影响因子：
11.1
作者：
Frey, M;Stettner, C;Gierl, A
通讯作者：
Gierl, A
影响因子：
1.7
作者：
BENTLEY, MD;MCDANIEL, IN;MAYNARD, R
通讯作者：
MAYNARD, R