Anticancer Properties of Essential Oils and Other Natural Products.
Anticancer Properties of Essential Oils and Other Natural Products.
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DOI：
10.1155/2018/3149362
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Pires IM
中科院分区：
文献类型：
--
作者：
Blowman K;Magalhães M;Lemos MFL;Cabral C;Pires IM
精油是次生代谢产物，在植物保护中起着关键作用，主要由具有挥发性和多种化学结构的萜烯组成。精油具有广泛的生物活性，特别是抗菌活性，长期以来一直被用于治疗各种人类疾病。癌细胞的预防和细胞毒性是通过广泛的作用机制表现出来的，最近的研究主要集中在特定精油主要成分和次要成分之间的协同和拮抗活性。精油已被证明具有癌细胞靶向活性，能够提高常用化疗药物的疗效，包括紫杉醇和多西紫杉醇，在给癌症患者服用时也显示出免疫功能。本综述是对EOs作为体内和体外抗癌药物应用的最新研究综述。癌细胞靶向特异性和使用EOs联合常规化疗策略也进行了探讨。
Essential oils are secondary metabolites with a key-role in plants protection, consisting primarily of terpenes with a volatile nature and a diverse array of chemical structures. Essential oils exhibit a wide range of bioactivities, especially antimicrobial activity, and have long been utilized for treating various human ailments and diseases. Cancer cell prevention and cytotoxicity are exhibited through a wide range of mechanisms of action, with more recent research focusing on synergistic and antagonistic activity between specific essential oils major and minor components. Essential oils have been shown to possess cancer cell targeting activity and are able to increase the efficacy of commonly used chemotherapy drugs including paclitaxel and docetaxel, having also shown proimmune functions when administered to the cancer patient. The present review represents a state-of-the-art review of the research behind the application of EOs as anticancer agents both in vitro and in vivo. Cancer cell target specificity and the use of EOs in combination with conventional chemotherapeutic strategies are also explored.
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DOI：
10.1155/2014/651593
发表时间：
2014
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Bilia AR;Guccione C;Isacchi B;Righeschi C;Firenzuoli F;Bergonzi MC
通讯作者：
Bergonzi MC
影响因子：
7.9
作者：
Arunasree, K. M.
通讯作者：
Arunasree, K. M.
影响因子：
2.7
作者：
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通讯作者：
Ofir, R
影响因子：
4
作者：
Dehnel, Nathalie;Moral, Javier;Bruenet, Bernhard
通讯作者：
Bruenet, Bernhard
影响因子：
0.8
作者：
Silva, Saulo Luís da;Chaar, Jamal da Silva;Yano, Tomomasa
通讯作者：
Yano, Tomomasa