The association between physical activity and the risk of incident psoriasis.
The association between physical activity and the risk of incident psoriasis.
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DOI：
10.1001/archdermatol.2012.943
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发表时间：
2012-08
影响因子：
--
通讯作者：
Qureshi, Abrar A.
中科院分区：
文献类型：
--
作者：
Frankel, Hillary C.;Han, Jiali;Li, Tricia;Qureshi, Abrar A.
研究女性总体体力活动、步行和剧烈运动与银屑病发病率之间的关系。队列研究。护士健康研究II，在一九九一年调查了116 430名年龄介乎27至44岁的妇女。研究人群包括86655名美国女护士，她们报告是否曾被诊断为牛皮癣，并在1991年、1997年和2001年完成了详细的体力活动问卷。我们排除了1991年前有牛皮癣病史的参与者。患牛皮癣的风险由身体活动的五分之一来衡量，由代谢等值任务分数来衡量。我们记录了1 195 703人年(1991-2005年14年)中发生的1026例银屑病病例。在调整了年龄、吸烟和饮酒后，增加体力活动与患牛皮癣的风险成反比。与最不活跃的五分位数相比，最活跃的五分位数的女性患银屑病的多变量相对风险(RR)较低(0.72[95%CI，0.59-0.89；P<；.001 for Trend])。剧烈的体力活动(相当于≥6代谢物)与牛皮癣风险的降低有关(最高五分之一的多变量RR为0.66[95%可信区间为0.54-0.81；P<；趋势为.001])；在调整了体重指数后，这种关联仍然显著(RR为0.73[95%可信区间为0.60-0.90；P=0.009为趋势区间])。步行与患牛皮癣的风险无关。在550例确诊的牛皮癣患者中，我们观察到与剧烈运动有关的牛皮癣风险也有类似的降低(最高五分之一的多变量RR为0.64[95%CI，0.48-0.86；P=0.03趋势])。在这项对美国女性的研究中，剧烈的体力活动与牛皮癣发病风险的降低独立相关。
To examine the association between total physical activity, walking, and vigorous exercise and the incidence of psoriasis in women. Cohort study. The Nurses’ Health Study II, a cohort of 116 430 women aged 27 to 44 years in 1991. The study population included 86 655 US female nurses who reported whether they had ever been diagnosed as having psoriasis and who completed detailed physical activity questionnaires in 1991, 1997, and 2001. We excluded participants with a history of psoriasis prior to 1991. Risk of psoriasis by quintile of physical activity as measured by a metabolic equivalent task score. We documented 1026 incident psoriasis cases during 1 195 703 person-years of follow-up (14 years, 1991–2005). After adjusting for age, smoking, and alcohol use, increasing physical activity was inversely associated with the risk of psoriasis. The most physically active quintile of women had a lower multivariate relative risk (RR) of psoriasis (0.72 [95% CI, 0.59–0.89; P <.001 for trend]) compared with the least active quintile. Vigorous physical activity (≥6 metabolic equivalents) was associated with a reduced risk of psoriasis (multivariate RR for the highest quintile, 0.66 [95% CI, 0.54–0.81; P <.001 for trend]); this association remained significant after adjusting for body mass index (RR, 0.73 [95% CI, 0.60–0.90; P =.009 for trend]). Walking was not associated with psoriasis risk. In a subset of 550 confirmed psoriasis cases, we observed a similarly reduced risk of psoriasis associated with vigorous physical activity (multivariate RR for the highest quintile, 0.64 [95% CI, 0.48–0.86; P =.03 for trend]). In this study of US women, vigorous physical activity is independently associated with a reduced risk of incident psoriasis.
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影响因子：
120.7
作者：
Gelfand, Joel M.;Neimann, Andrea L.;Troxel, Andrea B.
通讯作者：
Troxel, Andrea B.
牛皮癣与糖尿病和高血压的风险：一项针对美国女护士的前瞻性研究。
影响因子：
--
作者：
Qureshi, Abrar A.;Choi, Hyon K.;Setty, Arathi R.;Curhan, Gary C.
通讯作者：
Curhan, Gary C.
影响因子：
9.8
作者：
Polak, Jan;Klimcakova, Eva;Stich, Vladimir
通讯作者：
Stich, Vladimir
DOI：
10.1111/j.1600-0838.2006.00602.x
发表时间：
2007-10-01
影响因子：
4.1
作者：
Fischer, C. P.;Berntsen, A.;Pedersen, B. K.
通讯作者：
Pedersen, B. K.
影响因子：
10.3
作者：
Dominguez, P. L.;Assarpour, A.;Qureshi, A. A.
通讯作者：
Qureshi, A. A.