Cortical state and attention.

Cortical state and attention.
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DOI:
10.1038/nrn3084
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发表时间:
2011-08-10
影响因子:
34.7
通讯作者:
Thiele, Alexander
Thiele, Alexander
中科院分区:
医学1区
文献类型:
--
作者:
Harris, Kenneth D.;Thiele, Alexander

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大脑不断地调整其处理机制以适应行为需求。为了实现这一目标,它快速调节皮质电路的操作模式,控制信息转换和路由的方式。本文将重点关注研究皮层信息处理控制的两种实验方法:啮齿动物状态依赖性皮层处理的研究和灵长类动物视觉系统的注意力。这两个过程都涉及低频活动波动和尖峰相关性的调节,并由共同的受体系统介导。我们认为选择性注意涉及类似于状态变化的过程,在局部柱状级别上运行,以增强其他不显着特征的表示,同时抑制内部生成的活动模式。
The brain continuously adapts its processing machinery to behavioural demands. To achieve this it rapidly modulates the operating mode of cortical circuits, controlling the way information is transformed and routed. This article will focus on two experimental approaches by which the control of cortical information processing has been investigated: the study of state-dependent cortical processing in rodents, and attention in the primate visual system. Both processes involve a modulation of low-frequency activity fluctuations and spiking correlation, and are mediated by common receptor systems. We suggest that selective attention involves processes similar to state change, operating at a local columnar level to enhance the representation of otherwise nonsalient features while suppressing internally generated activity patterns.
任务难度调节初级视觉皮层中特定神经元群的活动。
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