wMel replacement of dengue-competent mosquitoes is robust to near-term change.
wMel replacement of dengue-competent mosquitoes is robust to near-term change.
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DOI:
10.1038/s41558-023-01746-w
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发表时间:
2023
影响因子:
30.7
通讯作者:
Marshall, John M.
中科院分区:
文献类型:
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作者:
Vasquez, Valeri N.;Kueppers, Lara M.;Rasic, Gordana;Marshall, John M.
Rising temperatures are impacting the range and prevalence of mosquito-borne diseases. A promising biocontrol technology replaces wild mosquitoes with those carrying the virus-blocking Wolbachia bacterium. Because the most widely used strain, wMel, is adversely affected by heat stress, we examined how global warming may influence wMel-based replacement. We simulated interventions in two locations with successful field trials using Coupled Model Intercomparison Project Phase 5 climate projections and historical temperature records, integrating empirical data on wMel’s thermal sensitivity into a model of Aedes aegypti population dynamics to evaluate introgression and persistence over one year. We show that in Cairns, Australia, climatic futures necessitate operational adaptations for heatwaves exceeding two weeks. In Nha Trang, Vietnam, projected heatwaves of three weeks and longer eliminate wMel under the most stringent assumptions of that symbiont’s thermal limits. We conclude that this technology is generally robust to near-term (2030s) climate change. Accelerated warming may challenge this in the 2050s and beyond. The biocontrol technology (wMel) used to mitigate mosquito-borne viruses is adversely affected by heat stress. The authors integrate empirical data on mosquito population dynamics and wMel thermal sensitivity to show that the technology is generally robust to near-term climate change.
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影响因子:
3
作者:
Hancock, Penny A.;Godfray, H. Charles J.
通讯作者:
Godfray, H. Charles J.
DOI:
10.1073/pnas.2106828118
发表时间:
2021-10-12
影响因子:
11.1
作者:
Beebe NW;Pagendam D;Trewin BJ;Boomer A;Bradford M;Ford A;Liddington C;Bondarenco A;De Barro PJ;Gilchrist J;Paton C;Staunton KM;Johnson B;Maynard AJ;Devine GJ;Hugo LE;Rasic G;Cook H;Massaro P;Snoad N;Crawford JE;White BJ;Xi Z;Ritchie SA
通讯作者:
Ritchie SA
DOI:
10.1016/s0140-6736(15)00417-1
发表时间:
2016-04-23
期刊:
Lancet (London, England)
影响因子:
--
作者:
Hemingway J;Ranson H;Magill A;Kolaczinski J;Fornadel C;Gimnig J;Coetzee M;Simard F;Roch DK;Hinzoumbe CK;Pickett J;Schellenberg D;Gething P;Hoppé M;Hamon N
通讯作者:
Hamon N
影响因子:
5.2
作者:
Caminade C;McIntyre KM;Jones AE
通讯作者:
Jones AE
影响因子:
4.5
作者:
通讯作者:
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