Socioeconomic status, race and COPD health outcomes.
Socioeconomic status, race and COPD health outcomes.
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DOI：
10.1136/jech.2009.089722
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发表时间：
2011-01
影响因子：
6.3
通讯作者：
Iribarren C
中科院分区：
文献类型：
--
作者：
Eisner MD;Blanc PD;Omachi TA;Yelin EH;Sidney S;Katz PP;Ackerson LM;Sanchez G;Tolstykh I;Iribarren C
虽然COPD是死亡和残疾的常见原因，但对社会经济地位（SES）和种族对健康结果的影响知之甚少。我们的目的是确定SES和种族对COPD严重程度状态、功能限制和COPD急性加重的独立影响。数据来自于对1，202名患有COPD的Kaiser Permanente北方加州医疗护理计划成员进行的FLOW队列研究。在横断面分析中，较低的教育程度和家庭收入始终与疾病严重程度较高、肺功能较差和身体功能受限较大相关。黑人与COPD严重程度相关，但在控制SES变量和其他协变量（合并症、吸烟、体重指数和职业暴露）后，这些差异不再明显。较低的教育程度和收入与COPD急性加重的预期风险较高独立相关（HR 1.5; 95% CI 1.01 - 2.1; HR 2.1; 95% CI 1.4 - 3.4）。低SES是一系列不良COPD健康结局的风险因素。临床医生和疾病管理计划应考虑SES作为一个关键的患者水平的风险指标，为不良结局。
Although COPD is a common cause of death and disability, little is known about the effects of socioeconomic status (SES) and race-ethnicity on health outcomes. We aimed to determine the independent impacts of SES and race-ethnicity on COPD severity status, functional limitations, and acute exacerbations of COPD among patients with access to health care. Data were used from the FLOW cohort study of 1,202 Kaiser Permanente Northern California Medical Care Plan members with COPD. Lower educational attainment and household income were consistently related to greater disease severity, poorer lung function, and greater physical functional limitations in cross-sectional analysis. Black race was associated with greater COPD severity, but these differences were no longer apparent after controlling for SES variables and other covariates (comorbidities, smoking, body mass index, and occupational exposures). Both lower education and income were independently related to a greater prospective risk of acute COPD exacerbation (HR 1.5; 95% CI 1.01 to 2.1; and HR 2.1; 95% CI 1.4 to 3.4, respectively). Low SES is a risk factor for a broad array of adverse COPD health outcomes. Clinicians and disease management programs should consider SES as a key patient-level marker of risk for poor outcomes.
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影响因子：
10
作者：
Blanc PD;Iribarren C;Trupin L;Earnest G;Katz PP;Balmes J;Sidney S;Eisner MD
通讯作者：
Eisner MD
影响因子：
5.9
作者：
Eisner, Mark D.;Yelin, Edward H.;Blanc, Paul D.
通讯作者：
Blanc, Paul D.
影响因子：
5.8
作者：
Eisner MD;Katz PP;Yelin EH;Shiboski SC;Blanc PD
通讯作者：
Blanc PD
影响因子：
2.9
作者：
Flegal, KM
通讯作者：
Flegal, KM
影响因子：
5.9
作者：
Eisner, Mark D.;Blanc, Paul D.;Yelin, Edward H.;Sidney, Stephen;Katz, Patricia P.;Ackerson, Lynn;Lathon, Phenius;Tolstykh, Irina;Omachi, Theodore;Byl, Nancy;Iribarren, Carlos
通讯作者：
Iribarren, Carlos