Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.
Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains.
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DOI:
10.1039/c3cc42709a
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发表时间:
2013-09-21
期刊:
影响因子:
--
通讯作者:
Dennison C
中科院分区:
文献类型:
--
作者:
Badarau A;Baslé A;Firbank SJ;Dennison C
The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. The copper metallochaperone Atx1 and the N-terminal metal-binding domain of a copper-transporting ATP-ase can form tight Zn(ii)-mediated hetero-complexes in both cyanobacteria and humans. Copper and zinc homeostasis could be linked by metal binding to these CXXC-containing proteins.
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