Organization of neural circuits underlying social behavior: A consideration of the medial amygdala.

Organization of neural circuits underlying social behavior: A consideration of the medial amygdala.
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社会行为背后的神经回路的组织:对内侧杏仁核的考虑。

DOI:
10.1016/j.conb.2021.02.008
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发表时间:
2021-06
影响因子:
5.7
通讯作者:
Hong W
Hong W
中科院分区:
医学2区
文献类型:
--
作者:
Raam T;Hong W

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内侧杏仁核(MeA)对于广泛的社会行为的表达至关重要,并且还与许多其他介导这些相同行为的大脑区域相连。在这里,我们总结了最近的进展,阐明机制,使MeA调节的社会行为的多样性,并考虑什么样的作用,MeA中发挥更广泛的网络区域,编排社会感觉运动的转变。我们概述的分子,解剖学和电生理功能的MeA隔离不同的社会行为,提出实验策略,以消除歧义的感觉表征的行为功能的背景下,社会互动,并考虑在何种程度上MeA功能可能与其他地区介导类似的行为重叠。
The medial amygdala (MeA) is critical for the expression of a broad range of social behaviors, and is also connected to many other brain regions that mediate those same behaviors. Here, we summarize recent advances towards elucidating mechanisms that enable the MeA to regulate a diversity of social behaviors, and also consider what role the MeA plays within the broader network of regions that orchestrate social sensorimotor transformations. We outline the molecular, anatomical, and electrophysiological features of the MeA that segregate distinct social behaviors, propose experimental strategies to disambiguate sensory representations from behavioral function in the context of a social interaction, and consider to what extent MeA function may overlap with other regions mediating similar behaviors.
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