Improved memory for information learnt before alcohol use in social drinkers tested in a naturalistic setting.
Improved memory for information learnt before alcohol use in social drinkers tested in a naturalistic setting.
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DOI：
10.1038/s41598-017-06305-w
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发表时间：
2017-07-24
影响因子：
4.6
通讯作者：
Morgan CJA
中科院分区：
文献类型：
--
作者：
Carlyle M;Dumay N;Roberts K;McAndrew A;Stevens T;Lawn W;Morgan CJA
酒精是已知的，以促进记忆，如果在实验室学习信息后给予;我们的目的是调查是否可以发现这种效果时，酒精消耗在一个自然的设置。88名社交饮酒者被随机分配到酒精自我剂量或清醒状态。该研究使用两个独立的任务评估了逆行易化和酒精诱导的记忆障碍。在逆行任务中，参与者在自己家中学习信息，然后随意饮酒。然后，参与者进行了一个顺行性记忆任务的酒精损伤时喝醉了。第二天，两项记忆任务再次完成。晚上平均饮酒量为82.59克。对于逆行任务，正如预测的那样，这两种条件在学习后立即（醉酒前）的记忆任务上表现出相似的表现，但在酒精条件下编码后的第二天早上测试时，表现更好。顺行任务没有显示饮酒后记忆表现的显着差异。饮酒量与第二天早上的逆行易化量呈正相关。这些研究结果证明了自然环境中的逆行促进效应，并发现它与自我管理的酒精克数有关。
Alcohol is known to facilitate memory if given after learning information in the laboratory; we aimed to investigate whether this effect can be found when alcohol is consumed in a naturalistic setting. Eighty-eight social drinkers were randomly allocated to either an alcohol self-dosing or a sober condition. The study assessed both retrograde facilitation and alcohol induced memory impairment using two independent tasks. In the retrograde task, participants learnt information in their own homes, and then consumed alcohol ad libitum. Participants then undertook an anterograde memory task of alcohol impairment when intoxicated. Both memory tasks were completed again the following day. Mean amount of alcohol consumed was 82.59 grams over the evening. For the retrograde task, as predicted, both conditions exhibited similar performance on the memory task immediately following learning (before intoxication) yet performance was better when tested the morning after encoding in the alcohol condition only. The anterograde task did not reveal significant differences in memory performance post-drinking. Units of alcohol drunk were positively correlated with the amount of retrograde facilitation the following morning. These findings demonstrate the retrograde facilitation effect in a naturalistic setting, and found it to be related to the self-administered grams of alcohol.
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影响因子：
4.4
作者：
Lyvers, Michael;Tobias-Webb, Juliette
通讯作者：
Tobias-Webb, Juliette
DOI：
10.1111/j.1530-0277.1995.tb01580.x
发表时间：
1995-06-01
影响因子：
3.2
作者：
GIVENS, B
通讯作者：
GIVENS, B
影响因子：
2.9
作者：
LAMBERTY, GJ;BECKWITH, BE;ROSS, AR
通讯作者：
ROSS, AR
影响因子：
2.1
作者：
Flowe, Heather D.;Smith, Harriet M. J.;Rai, Lovedeep
通讯作者：
Rai, Lovedeep
影响因子：
15.9
作者：
Mednick, Sara C.;Cai, Denise J.;Shuman, Tristan;Anagnostaras, Stephan;Wixted, John T.
通讯作者：
Wixted, John T.