Machine learning enables non-Gaussian investigation of changes to peripheral nerves related to electrical stimulation.
Machine learning enables non-Gaussian investigation of changes to peripheral nerves related to electrical stimulation.
复制标题
机器学习能够对与电刺激相关的周围神经的变化进行非高斯调查。
DOI:
10.1038/s41598-024-53284-w
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发表时间:
2024-02-02
影响因子:
4.6
通讯作者:
中科院分区:
文献类型:
--
作者:
Electrical stimulation of the peripheral nervous system (PNS) is becoming increasingly important for the therapeutic treatment of numerous disorders. Thus, as peripheral nerves are increasingly the target of electrical stimulation, it is critical to determine how, and when, electrical stimulation results in anatomical changes in neural tissue. We introduce here a convolutional neural network and support vector machines for cell segmentation and analysis of histological samples of the sciatic nerve of rats stimulated with varying current intensities. We describe the methodologies and present results that highlight the validity of the approach: machine learning enabled highly efficient nerve measurement collection, while multivariate analysis revealed notable changes to nerves’ anatomy, even when subjected to levels of stimulation thought to be safe according to the Shannon current limits.
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DOI:
10.1002/jbm.b.31223
发表时间:
2009-05
期刊:
Journal of biomedical materials research. Part B, Applied biomaterials
影响因子:
--
作者:
Cogan SF;Ehrlich J;Plante TD;Smirnov A;Shire DB;Gingerich M;Rizzo JF
通讯作者:
Rizzo JF
影响因子:
64.8
作者:
Harris CR;Millman KJ;van der Walt SJ;Gommers R;Virtanen P;Cournapeau D;Wieser E;Taylor J;Berg S;Smith NJ;Kern R;Picus M;Hoyer S;van Kerkwijk MH;Brett M;Haldane A;Del Río JF;Wiebe M;Peterson P;Gérard-Marchant P;Sheppard K;Reddy T;Weckesser W;Abbasi H;Gohlke C;Oliphant TE
通讯作者:
Oliphant TE
影响因子:
4.5
作者:
Johnson RL;Wilson CG
通讯作者:
Wilson CG
影响因子:
5.3
作者:
Duncan, Ian D.;Radcliff, Abigail B.
通讯作者:
Radcliff, Abigail B.
影响因子:
4
作者:
McCreery D;Pikov V;Troyk PR
通讯作者:
Troyk PR