HIV incidence among men who have sex with men in mainland China: a systematic review protocol.

HIV incidence among men who have sex with men in mainland China: a systematic review protocol.
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大陆男男性行为者中艾滋病病毒感染率中国:一项系统评价方案。

DOI:
10.1186/s13643-021-01828-w
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发表时间:
2021-10-27
期刊:
影响因子:
3.7
通讯作者:
Siegler AJ
Siegler AJ
中科院分区:
医学4区
文献类型:
--
作者:
Huang W;Wang L;Guodong M;Zahn RJ;Taussig J;Peterson SR;Baral S;Moore RH;Huang X;Hou J;Sullivan PS;Siegler AJ

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在中国,男男性行为者(MSM)感染艾滋病毒的比例过高。在全球范围内,年轻的男男性行为者发生艾滋病毒感染的风险较高,但中国大陆男男性行为者年龄分层艾滋病毒发病率的估计值存在很大差异,这可能是由于流行病性质的区域差异。鉴于需要高质量的流行病学数据来实现到2030年消除新发艾滋病毒感染的全球目标,本系统性综述和荟萃分析旨在确定中国大陆的年龄分层艾滋病毒发病率,包括地理区域和时间的考虑。本综述将包括中国大陆男男性行为者中已报告HIV感染的纵向研究、横断面调查和监测报告。我们将在英文和中文文献数据库中检索2003年1月1日至2020年4月30日期间发表的研究和报告。对于每项研究,两名审查员将独立筛选,确定合格性,并提取相关数据,通过第三名审查员的共识解决差异。纳入研究的方法学质量将通过观察性研究系统评价评分质量评估工具(QATSO)进行评估。我们将根据地理差异和时间趋势对艾滋病毒发病率进行年龄分层估计。将使用适用于数据集的统计技术检查异质性。对于亚组分析,我们将进行混合效应荟萃分析模型。通过对中国大陆男男性接触者艾滋病发病率的年龄分层估计,并结合地理和时间变化,有助于更好地了解中国大陆男男性接触者艾滋病的流行情况。研究结果将反映流行动态,为地方和国家艾滋病预防干预计划和政策提供信息,并为中国MSM未来的研究提供估计数据。PROSPERO ID 154834
Men who have sex with men (MSM) are disproportionately affected by HIV in China. Globally, younger MSM are at higher risk for incident HIV infections, but there has been substantial variation in the estimates of age-stratified HIV incidence among MSM in mainland China, potentially due to regional differences in the nature of the epidemic. Given the need for quality epidemiological data to meet the global goal of ending new HIV infections by 2030, this systematic review and meta-analysis aims to determine age-stratified HIV incidence in mainland China, including consideration by geographic region and time. This review will include longitudinal studies, cross-sectional surveys, and surveillance reports among MSM in mainland China that have reported HIV incidence. We will search studies and reports published from January 1, 2003, to April 30, 2020, in both English and Chinese language literature databases. For each study considered, two reviewers will independently screen, determine eligibility, and extract relevant data, with discrepancies resolved by consensus of a third reviewer. The methodological quality of included studies will be assessed by the Quality Assessment Tool for Systematic Reviews of Observational Studies Score (QATSO). We will develop age-stratified estimates of HIV incidence with geographic variations and temporal trends. Heterogeneity will be examined using statistical techniques appropriate to the dataset. For subgroup analyses, we will conduct mixed-effects meta-analysis models. This review will contribute to a better understanding of the HIV epidemic among MSM in mainland China by providing age-stratified estimates of HIV incidence with a portrayal of geographic and temporal variations. Findings will reflect epidemic dynamics, informing local and national intervention programs and policies for HIV prevention, and providing estimation data to inform future research among MSM in China. PROSPERO ID 154834
DOI: 10.1371/journal.pone.0201953
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期刊: PloS one
影响因子: 3.7
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影响因子: 5.6
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影响因子: 4.4
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通讯作者: Holtz TH