Functional Connectivity of the Chemosenses: A Review.
Functional Connectivity of the Chemosenses: A Review.
复制标题
化学的功能连通性:评论。
DOI:
10.3389/fnsys.2022.865929
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发表时间:
2022
影响因子:
3
通讯作者:
Scheinost, Dustin
中科院分区:
文献类型:
--
作者:
Farruggia, Michael C.;Pellegrino, Robert;Scheinost, Dustin
Functional connectivity approaches have long been used in cognitive neuroscience to establish pathways of communication between and among brain regions. However, the use of these analyses to better understand how the brain processes chemosensory information remains nascent. In this review, we conduct a literature search of all functional connectivity papers of olfaction, gustation, and chemesthesis, with 103 articles discovered in total. These publications largely use approaches of seed-based functional connectivity and psychophysiological interactions, as well as effective connectivity approaches such as Granger Causality, Dynamic Causal Modeling, and Structural Equation Modeling. Regardless of modality, studies largely focus on elucidating neural correlates of stimulus qualities such as identity, pleasantness, and intensity, with task-based paradigms most frequently implemented. We call for further “model free” or data-driven approaches in predictive modeling to craft brain-behavior relationships that are free from a priori hypotheses and not solely based on potentially irreproducible literature. Moreover, we note a relative dearth of resting-state literature, which could be used to better understand chemosensory networks with less influence from motion artifacts induced via gustatory or olfactory paradigms. Finally, we note a lack of genomics data, which could clarify individual and heritable differences in chemosensory perception.
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影响因子:
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作者:
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通讯作者:
Lundström JN
影响因子:
6.8
作者:
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影响因子:
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4.8
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通讯作者:
Li, Yonggang
影响因子:
6.8
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通讯作者:
Pryor TL