Evo-devo and the primate isocortex: the central organizing role of intrinsic gradients of neurogenesis.
Evo-devo and the primate isocortex: the central organizing role of intrinsic gradients of neurogenesis.
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DOI：
10.1159/000365181
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Finlay BL
中科院分区：
文献类型：
--
作者：
Charvet CJ;Finlay BL
细胞发生、细胞类型规范和树突成熟等基本过程的启动和终止的空间梯度在发育中的神经系统中普遍存在。这种梯度可以在特定物种中产生生态位适应。例如，一些脊椎动物视网膜的“中央区域”中光感受器和神经元的高密度是由于其中心相对于其外围较早成熟的结果。在不同物种中，大脑区域异速生长的规律性可以源自保守的空间梯度：与神经管基底板相比，鼻翼中较长的神经发生与较大大脑中鼻翼板衍生物相对较大的扩张有关。我们描述了同皮质内神经发生的梯度及其对物种内和物种间成体细胞结构的影响。尾侧同皮质的神经发生持续时间较长与相对于头侧同皮质的神经元数量和每列神经元密度的增加有关。单个神经元的晚熟特征，例如体大小和树突棘数量反映了这种梯度。考虑到啮齿类动物和灵长类动物，每个物种的同皮质神经发生持续时间越长，每列神经元数量和密度的头侧到尾侧差异就越大。延长的发育持续时间会在较大大脑中的同皮质结构中产生实质性的、可预测的变化，并且可能会导致功能组织逐渐发生变化，其特性我们尚未完全了解。以前被视为物种或生态位特异性适应的等皮质结构的许多特征现在可以被整合为部署在更大大脑中的时空梯度的自然结果。
Spatial gradients in the initiation and termination of basic processes, such as cytogenesis, cell-type specification and dendritic maturation are ubiquitous in developing nervous systems. Such gradients can produce a niche adaptation in a particular species. For example, the high density of photoreceptors and neurons in the “area centralis” of some vertebrate retinas result from the early maturation of its center relative to its periphery. Across species, regularities in allometric scaling of brain regions can derive from conserved spatial gradients: longer neurogenesis in the alar versus the basal plate of the neural tube is associated with relatively greater expansion of alar plate derivatives in larger brains. We describe gradients of neurogenesis within the isocortex and their effects on adult cytoarchitecture within and across species. Longer duration of neurogenesis in the caudal isocortex is associated with increased neuron number and density per column relative to the rostral isocortex. Later-maturing features of single neurons, such as soma size and dendritic spine numbers reflect this gradient. Considering rodents and primates, the longer duration of isocortical neurogenesis in each species, the greater the rostral-to-caudal difference in neuron number and density per column. Extended developmental duration produces substantial, predictable changes in the architecture of the isocortex in larger brains, and presumably, a progressively changed functional organization whose properties we do not yet fully understand. Many features of isocortical architecture previously viewed as species- or niche-specific adaptations can now be integrated as the natural outcomes of spatiotemporal gradients that are deployed in larger brains.
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DOI：
10.1073/pnas.1010356107
发表时间：
2010-09-07
影响因子：
11.1
作者：
Collins, Christine E.;Airey, David C.;Kaas, Jon H.
通讯作者：
Kaas, Jon H.
影响因子：
25
作者：
Catania, KC
通讯作者：
Catania, KC
DOI：
10.1111/j.1749-6632.2011.05991.x
发表时间：
2011-01-01
期刊：
NEW PERSPECTIVES ON NEUROBEHAVIORAL EVOLUTION
影响因子：
--
作者：
Bianchi, Serena;Bauernfeind, Amy L.;Sherwood, Chet C.
通讯作者：
Sherwood, Chet C.
灵长类同皮质神经元密度和数量的系统性平衡梯度。
影响因子：
2.9
作者：
Cahalane DJ;Charvet CJ;Finlay BL
通讯作者：
Finlay BL
影响因子：
3.3
作者：
Ballesteros-Yáñez, I;Benavides-Piccione, R;DeFelipe, J
通讯作者：
DeFelipe, J