Going beyond the mean in examining relationships of adolescent non-cognitive skills with health-related quality of life and biomarkers in later-life.
Going beyond the mean in examining relationships of adolescent non-cognitive skills with health-related quality of life and biomarkers in later-life.
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DOI：
10.1016/j.ehb.2020.100923
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发表时间：
2020-12
影响因子：
2.5
通讯作者：
Sutton M
中科院分区：
文献类型：
--
作者：
Atkins R;Turner AJ;Chandola T;Sutton M
我们使用主观和客观的健康测量方法，研究了青少年非认知技能与成人健康之间的关系。尽职尽责与应对压力的能力呈正相关，与心血管风险呈负相关。宜人性与健康相关的生活质量呈正相关，与生理“磨损”呈负相关，而与应对压力的能力呈负相关。神经质与健康相关的生活质量呈负相关，与生理磨损和心血管风险呈正相关。除了心血管风险生物标记物外，所有这些关联在健康分布结束时都更强，这表明健康状况较差。几项研究已经确定了早期非认知技能与晚年健康和健康行为之间的联系。然而，没有一项研究解决了更重要的政策关切，即这种关系如何在健康分布中变化。我们使用无条件分位数回归来分析青春期非认知技能对50岁时健康相关生活质量和45岁时生物标记物分布的影响。我们考察了国家儿童发展研究中3585名个体在16岁时记录的责任心、宜人性和神经质的测量结果。青少年的责任心与应对压力的能力呈正相关，与中年患心血管疾病的风险呈负相关。青春期的宜人性与较高的健康相关生活质量和较低的生理“磨损”有关，但与中年应对压力的能力呈负相关。青春期神经质与较低的健康相关生活质量、较高的生理“磨损”以及中年患心血管疾病的风险较高有关。除心血管风险生物标志物外，所有这些关联在健康分布的低端都更强。这些关联对于使用逆概率加权校正磨损是稳健的，并且与假设对可观测和不可观测进行比例选择的因果界限一致。他们建议，改善青春期非认知技能的政策可能会为那些健康状况最差的人提供最长期的健康益处。
We examined the association between adolescent non-cognitive skills and adult health, using both subjective and objective measures of health. Conscientiousness is positively associated with your ability to cope with stress and negatively associated with cardiovascular risk. Agreeableness is positively associated with health-related quality of life and negatively associated with physiological ‘wear and tear’, however is negatively associated with your ability to cope with stress. Neuroticism is negatively associated with health-related quality of life, and positively associated with physiological ‘wear and tear’ and cardiovascular risk. All of these associations are stronger at the end of the health distribution that indicates poorer health, except for the cardiovascular risk biomarkers. Several studies have established associations between early-life non-cognitive skills and later-life health and health behaviours. However, no study addresses the more important policy concern about how this relationship varies along the health distribution. We use unconditional quantile regression to analyse the effects of adolescent non-cognitive skills across the distributions of the health-related quality of life at age 50 and biomarkers at age 45 years. We examine the effects of measures of conscientiousness, agreeableness and neuroticism recorded at age 16 for 3585 individuals from the National Child Development Study. Adolescent conscientiousness is positively associated with ability to cope with stress and negatively associated with risk of cardiovascular disease in middle-age. Adolescent agreeableness is associated with higher health-related quality of life and lower physiological ‘wear and tear’, but negatively associated with ability to cope with stress in middle-age. Adolescent neuroticism is associated with lower health-related quality of life, higher physiological ‘wear and tear’, and a higher risk of cardiovascular disease in middle-age. All of these associations are stronger at the lower end of the health distribution except for the cardiovascular risk biomarkers. These associations are robust to correcting for attrition using inverse probability weighting and consistent with causal bounds assuming proportional selection on observables and unobservables. They suggest policies that improve non-cognitive skills in adolescence could offer most long-term health benefit to those with the poorest health.
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DOI：
10.1158/1055-9965.epi-14-0064
发表时间：
2014-09
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Brenner DR;Scherer D;Muir K;Schildkraut J;Boffetta P;Spitz MR;Le Marchand L;Chan AT;Goode EL;Ulrich CM;Hung RJ
通讯作者：
Hung RJ
影响因子：
13.6
作者：
Castagné R;Garès V;Karimi M;Chadeau-Hyam M;Vineis P;Delpierre C;Kelly-Irving M;Lifepath Consortium
通讯作者：
Lifepath Consortium
影响因子：
4.7
作者：
Baba, Camilla;Kearns, Ade;Lewsey, James
通讯作者：
Lewsey, James
影响因子：
10.7
作者：
Bitler, Marianne P.;Gelbach, Jonah B.;Hoynes, Hilary W.
通讯作者：
Hoynes, Hilary W.
昼夜皮质醇斜率以及心理和身体健康结果：系统评价和荟萃分析。
影响因子：
3.7
作者：
Adam EK;Quinn ME;Tavernier R;McQuillan MT;Dahlke KA;Gilbert KE
通讯作者：
Gilbert KE