Brain gray matter structures associated with trait impulsivity: A systematic review and voxel-based meta-analysis.

Brain gray matter structures associated with trait impulsivity: A systematic review and voxel-based meta-analysis.
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与特质冲动相关的大脑灰质结构:系统回顾和基于体素的荟萃分析

DOI:
10.1002/hbm.25361
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发表时间:
2021-05
影响因子:
4.8
通讯作者:
Gong Q
Gong Q
中科院分区:
医学2区
文献类型:
--
作者:
Pan N;Wang S;Zhao Y;Lai H;Qin K;Li J;Biswal BB;Sweeney JA;Gong Q

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性格冲动是一种多方面的人格特征,有助于适应性的生活结果,尽管越来越多的神经成像研究已经调查了性格冲动的结构相关性,但这些发现仍然是高度不一致的,我们进行了综合审查。灰质(GM)的性状冲动性和荟萃分析,以检查以前的全脑的同时发生基于体素的形态计量学研究总结了过去文献中GM形态的研究结果,并且定量荟萃分析显示了与脉冲相关的体积量的变化。年龄和性别在脉冲 - GM体积关联中的影响发现可能对冲动性相关的疾病的临床诊断和干预措施具有实际意义。 为了描述灰质底物的综合描述,我们进行了系统的审查和基于体素的荟萃分析,以发现前额叶,临时和壁皮层中的体积相关区域。以及与冲动性相关疾病的干预措施。
Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive life outcomes. Although a growing body of neuroimaging studies have investigated the structural correlates of trait impulsivity, the findings remain highly inconsistent and heterogeneous. Herein, we performed a systematic review to depict an integrated delineation of gray matter (GM) substrates of trait impulsivity and a meta‐analysis to examine concurrence across previous whole‐brain voxel‐based morphometry studies. The systematic review summarized the diverse findings in GM morphometry in the past literature, and the quantitative meta‐analysis revealed impulsivity‐related volumetric GM alterations in prefrontal, temporal, and parietal cortices. In addition, we identified the modulatory effects of age and gender in impulsivity‐GM volume associations. The present study advances understanding of brain GM morphometry features underlying trait impulsivity. The findings may have practical implications in the clinical diagnosis of and intervention for impulsivity‐related disorders.
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