Fish, mercury, selenium and cardiovascular risk: current evidence and unanswered questions.
Fish, mercury, selenium and cardiovascular risk: current evidence and unanswered questions.
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DOI：
10.3390/ijerph6061894
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发表时间：
2009-06
影响因子：
--
通讯作者：
Mozaffarian D
中科院分区：
文献类型：
--
作者：
Mozaffarian D
公众和媒体对成年人摄入鱼类对健康的影响产生了争议。大量证据表明，食用鱼类可降低冠心病死亡率，而冠心病是发达国家和大多数发展中国家的主要死因。相反，人们越来越担心某些鱼类接触汞的潜在影响。海鲜种类还富含硒，硒是一种基本的微量元素，可以防止心血管疾病和汞的毒性作用。这种保护作用将直接影响到关于硒最佳摄入量的建议，以及评估不同人群因摄入鱼类而接触汞的潜在影响。由于鱼类消费似乎对成年人的健康有重要的益处，因此阐明鱼类摄入量、汞和硒暴露与健康风险之间的关系具有相当大的科学和公共卫生意义。对成年人食用鱼类对健康影响的证据进行了审查，重点是证据的强度和一致性以及omega-3脂肪酸、汞和硒的相对影响程度。鉴于证据的优势，重点是心血管效应，但也简要审查了其他潜在的健康效应，以及多氯联苯和二恶英对鱼类的潜在影响。总结了目前存在的问题和进一步研究的方向。
Controversy has arisen among the public and in the media regarding the health effects of fish intake in adults. Substantial evidence indicates that fish consumption reduces coronary heart disease mortality, the leading cause of death in developed and most developing nations. Conversely, concerns have grown regarding potential effects of exposure to mercury found in some fish. Seafood species are also rich in selenium, an essential trace element that may protect against both cardiovascular disease and toxic effects of mercury. Such protective effects would have direct implications for recommendations regarding optimal selenium intake and for assessing the potential impact of mercury exposure from fish intake in different populations. Because fish consumption appears to have important health benefits in adults, elucidating the relationships between fish intake, mercury and selenium exposure, and health risk is of considerable scientific and public health relevance. The evidence for health effects of fish consumption in adults is reviewed, focusing on the strength and consistency of evidence and relative magnitudes of effects of omega-3 fatty acids, mercury, and selenium. Given the preponderance of evidence, the focus is on cardiovascular effects, but other potential health effects, as well as potential effects of polychlorinated biphenyls and dioxins in fish, are also briefly reviewed. The relevant current unanswered questions and directions of further research are summarized.
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影响因子：
--
作者：
Berges, R
通讯作者：
Berges, R
影响因子：
3.9
作者：
Ayaz, M;Ozdemir, S;Turan, B
通讯作者：
Turan, B
DOI：
10.1186/1476-069x-5-29
发表时间：
2006-10-10
期刊：
Environmental health : a global access science source
影响因子：
--
作者：
Fillion, Myriam;Mergler, Donna;Guimaraes, Jean Remy Davee
通讯作者：
Guimaraes, Jean Remy Davee
影响因子：
3.9
作者：
Frisk, P;Wester, K;Lindh, U
通讯作者：
Lindh, U
影响因子：
4.2
作者：
Foran, JA;Good, DH;Schwager, SJ
通讯作者：
Schwager, SJ