Formation of nano-bio-complex as nanomaterials dispersed in a biological solution for understanding nanobiological interactions.
Formation of nano-bio-complex as nanomaterials dispersed in a biological solution for understanding nanobiological interactions.
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纳米材料分散在生物溶液中形成纳米生物复合物，以了解纳米生物相互作用
DOI：
10.1038/srep00406
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发表时间：
2012
影响因子：
4.6
通讯作者：
Hanagata, Nobutaka
中科院分区：
文献类型：
--
作者：
Xu, Mingsheng;Li, Jie;Iwai, Hideo;Mei, Qingsong;Fujita, Daisuke;Su, Huanxing;Chen, Hongzheng;Hanagata, Nobutaka
Information on how cells interface with nanomaterials in biological environments has important implications for the practice of nanomedicine and safety consideration of nanomaterials. However, our current understanding of nanobiological interactions is still very limited. Here, we report the direct observation of nanomaterial bio-complex formation (other than protein corona) from nanomaterials dispersed in biologically relevant solutions. We observed highly selective binding of the components of cell culture medium and phosphate buffered saline to ZnO and CuO nanoparticles, independent of protein molecules. Our discoveries may provide new insights into the understanding of how cells interact with nanomaterials.
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影响因子：
17.1
作者：
Xia, Tian;Kovochich, Michael;Liong, Monty;Maedler, Lutz;Gilbert, Benjamin;Shi, Haibin;Yeh, Joanne I.;Zink, Jeffrey I.;Nel, Andre E.
通讯作者：
Nel, Andre E.
影响因子：
17.1
作者：
Chen, Alex M.;Taratula, Oleh;Wei, Dongguang;Yen, Hsin-I;Thomas, Thresia;Thomas, T. J.;Minko, Tamara;He, Huixin
通讯作者：
He, Huixin
影响因子：
7.8
作者：
Park S;Hamad-Schifferli K
通讯作者：
Hamad-Schifferli K
影响因子：
17.1
作者：
Casals, Eudald;Pfaller, Tobias;Puntes, Victor
通讯作者：
Puntes, Victor
影响因子：
17.1
作者：
Asati A;Santra S;Kaittanis C;Perez JM
通讯作者：
Perez JM