Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review.
Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review.
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DOI：
10.1038/s41598-021-92971-w
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发表时间：
2021-07-02
影响因子：
4.6
通讯作者：
Jiang B
中科院分区：
文献类型：
--
作者：
Zhang N;Wang J;Li Y;Jiang B
原发性开角型青光眼（POAG）是世界上不可逆失明的主要原因，并受到各种社会人口因素的影响。这项荟萃分析旨在确定过去 20 年来全球成人一般人群中 POAG 的患病率，并探讨按年龄、性别和地理位置划分的患病率变化。使用 PubMed、Embase 和 Web of Science 数据库进行电子文献检索。招募了过去 20 年（2000 年至 2020 年）发表的报告 POAG 患病率的基于人群的横断面或队列研究。通过荟萃分析选择并系统地审查符合规定资格标准的相关研究。根据各种危险因素分析 POAG 的患病率。随机效应模型用于荟萃分析。本次荟萃分析纳入了 50 篇出版物，总共 198,259 名受试者。全球 POAG 总体患病率为 2.4%（95% CI 2.0 ~ 2.8%）。患病率随着年龄的增长而增加。研究发现，男性比女性更容易患 POAG（RR 1.28，p<0.01）。非洲 POAG 患病率在各大洲中最高（4.0%）。目前估计全球 POAG 人口为 6856 万（95% CI 59.99 ~ 79.98）。 POAG 是一种全球范围内威胁视力的疾病，在过去 20 年中发病率很高。由于年龄、性别和人口地理位置等危险因素的差异，各个研究中 POAG 的人群患病率差异很大。
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness in the world and is influenced by various sociodemographic factors. This meta-analysis aims to determine the worldwide prevalence of POAG in the adult general population for the last 20 years, and explore variation in prevalence by age, gender and geographical location. An electronic literature search was performed using the PubMed, Embase, and Web of Science databases. Population-based cross-sectional or cohort studies published in the last 20 years (2000–2020) that reported prevalence of POAG were recruited. Relevant studies meeting defined eligibility criteria were selected and reviewed systematically by meta-analysis. The prevalence of POAG was analyzed according to various risk factors. A random effect model was used for the meta-analysis. Fifty publications with a total of 198,259 subjects were included in this meta-analysis. The worldwide overall prevalence of POAG was 2.4% (95% CI 2.0 ~ 2.8%). The prevalence increases with age. Men are found to be more susceptible to POAG than women (RR 1.28, p < 0.01). Africa is found to have the highest prevalence of POAG (4.0%) among all continents. The current estimated global population of POAG is 68.56 million (95% CI 59.99 ~ 79.98). POAG is a worldwide vision threatening disease with high prevalence for the last 20 years. The population-based prevalence of POAG varies widely across individual studies, due to variations in risk factors of age, gender, and population geographic location.
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DOI：
10.3233/jad-180416
发表时间：
2018
期刊：
Journal of Alzheimer's disease : JAD
影响因子：
--
作者：
Bacigalupo I;Mayer F;Lacorte E;Di Pucchio A;Marzolini F;Canevelli M;Di Fiandra T;Vanacore N
通讯作者：
Vanacore N
影响因子：
4.1
作者：
Bourne, RRA;Sukudom, P;Rojanapongpun, P
通讯作者：
Rojanapongpun, P
影响因子：
4.1
作者：
Casson, J.;Newland, H. S.;Aung, T.
通讯作者：
Aung, T.
影响因子：
4.1
作者：
Foster, P. J.;Broadway, D. C.;Khaw, K-T
通讯作者：
Khaw, K-T
影响因子：
4.1
作者：
Foster, PJ;Buhrmann, R;Johnson, GJ
通讯作者：
Johnson, GJ