Developmental Patterns of Child Emotion Dysregulation as Predicted by Serotonin Transporter Genotype and Parenting.

Developmental Patterns of Child Emotion Dysregulation as Predicted by Serotonin Transporter Genotype and Parenting.
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DOI:
10.1080/15374416.2017.1326120
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发表时间:
2018
期刊:
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
影响因子:
--
通讯作者:
Baker BL
Baker BL
中科院分区:
其他
文献类型:
--
作者:
Noroña AN;Tung I;Lee SS;Blacher J;Crnic KA;Baker BL

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情绪调节的个体差异对社会、学业、职业和心理发展至关重要,儿童期情绪调节障碍(艾德)是许多发展结果的危险因素。本研究旨在(a)描述艾德在幼儿期(3-6岁)的发展轨迹;(B)研究其对青少年5-羟色胺转运体基因型、积极和消极的父母行为及其相互作用的敏感性。参与者是99个家庭(审查时设盲),这是一项对有或没有发育迟缓的儿童进行的纵向研究。儿童艾德和早期养育的编码从亲子实验室的相互作用。为了研究5-羟色胺转运蛋白基因型作为父母养育和儿童艾德之间的调节因子,将纯合短(SS)基因型儿童与纯合长(LL)或杂合(SL)基因型儿童进行比较。我们使用潜在生长曲线模型(LGCM)来模拟3至6岁儿童艾德的年变化。LGCM显示,艾德在整个幼儿期总体下降。此外,我们观察到单独的基因型x积极和基因型x消极的父母教养行为的相互作用的预测艾德的增长曲线。SL/LL基因型儿童的艾德轨迹与积极和消极的父母教养行为关系最小,而SS基因型儿童的艾德在受到低消极父母教养或高积极父母教养时下降得更快。这些研究结果提供了证据的基因x环境相互作用的发展艾德的方式,在概念上是一致的Vantage敏感性,他们提高了前瞻性设计提供的推论。
Individual differences in emotion regulation are central to social, academic, occupational, and psychological development, and emotion dysregulation (ED) in childhood is a risk factor for numerous developmental outcomes. The present study aimed to (a) describe the developmental trajectory of ED across early childhood (3–6 years) and (b) examine its sensitivity to youth serotonin transporter genotype, positive and negative parenting behaviors, and their interaction. Participants were 99 families in the (masked for review), a longitudinal study of children with or without developmental delays. Child ED and early parenting were coded from parent-child laboratory interactions. To examine serotonin transporter genotype as a moderator between parenting and child ED, children with the homozygous short (SS) genotype were compared to children with the homozygous long (LL) or heterozygous (SL) genotype. We used Latent Growth Curve Modeling (LGCM) to model yearly change in ED from child age 3 to 6 years. LGCM revealed that ED decreased overall across early childhood. In addition, we observed separate genotype x positive and genotype x negative parenting behavior interactions in predictions of ED growth curves. Children with the SL/LL genotype had ED trajectories that were minimally related to positive and negative parenting behavior, whereas ED decreased more precipitously among children with the SS genotype when exposed to low negative parenting or high positive parenting. These findings provide evidence for gene x environment interactions in the development of ED in a manner that is conceptually consistent with vantage sensitivity, and they improve inferences afforded by prospective designs.
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