Cingulate cortex: diverging data from humans and monkeys.

Cingulate cortex: diverging data from humans and monkeys.
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DOI:
10.1016/j.tins.2009.07.001
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发表时间:
2009-11
影响因子:
15.9
通讯作者:
Botvinick M
Botvinick M
中科院分区:
医学1区
文献类型:
--
作者:
Cole MW;Yeung N;Freiwald WA;Botvinick M

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认知神经科学研究部分依赖于人类和非人类灵长类动物大脑之间的同源性。因此,当假定的解剖同源物表现出不同的功能特性时,就会出现一个困惑。这种情况最近出现在前扣带皮层(ACC)的情况下。在人类中,许多研究表明ACC在检测信息处理中的冲突中发挥作用。相比之下,对猕猴ACC的研究未能找到与冲突相关的反应。我们认为这种差异的几种解释,包括研究方法的差异和跨物种的功能神经解剖学差异。未来研究的新方向进行了概述,强调区分虚幻的跨物种的差异,使我们的物种独特的真正的进化差异的重要性。
Cognitive neuroscience research relies, in part, on homologies between the brains of human and non-human primates. A quandary therefore arises when presumed anatomical homologues exhibit different functional properties. Such a situation has recently arisen in the case of the anterior cingulate cortex (ACC). In humans, numerous studies suggest a role for ACC in detecting conflicts in information processing. Studies of macaque monkey ACC, in contrast, have failed to find conflict-related responses. We consider several interpretations of this discrepancy, including differences in research methodology and cross-species differences in functional neuroanatomy. New directions for future research are outlined, emphasizing the importance of distinguishing illusory cross-species differences from the true evolutionary differences that make our species unique.
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