Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic.
Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic.
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DOI：
10.1038/s41598-021-96987-0
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发表时间：
2021-09-01
影响因子：
4.6
通讯作者：
Dibattista M
中科院分区：
文献类型：
--
作者：
Cecchetto C;Di Pizio A;Genovese F;Calcinoni O;Macchi A;Dunkel A;Ohla K;Spinelli S;Farruggia MC;Joseph PV;Menini A;Cantone E;Dinnella C;Cecchini MP;D'Errico A;Mucignat-Caretta C;Parma V;Dibattista M
化学感应障碍已被确定为 COVID-19 的一个具体指标。它们影响大多数患者，并且可能在呼吸道症状消失后仍持续很长时间，这是前所未有的医学挑战。自 SARS-CoV-2 大流行开始以来，我们现在对与 COVID-19 相关的嗅觉、味觉和化学感觉丧失有了更多了解。然而，恢复的时间动态和特征仍然未知。在这里，我们利用全球化学感应研究联盟 (GCCR) 众包调查的数据，评估了意大利第一波大流行期间被诊断为 COVID-19 的参与者呼吸道症状消失后的化学感应能力。该分析确定了化学感应恢复的两种模式：部分恢复和实质性恢复，这两种模式被发现与年龄差异、化学感应丧失程度和区域模式有关。揭示从嗅觉、味觉和化学感觉障碍中恢复的自我报告现象学是第一步，也是至关重要的一步，为医疗保健专业人员提供采取有目的和有针对性的行动来解决化学感觉障碍及其严重不适的工具。
Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented medical challenge. Since the SARS-CoV-2 pandemic started, we now know much more about smell, taste, and chemesthesis loss associated with COVID-19. However, the temporal dynamics and characteristics of recovery are still unknown. Here, capitalizing on data from the Global Consortium for Chemosensory Research (GCCR) crowdsourced survey, we assessed chemosensory abilities after the resolution of respiratory symptoms in participants diagnosed with COVID-19 during the first wave of the pandemic in Italy. This analysis led to the identification of two patterns of chemosensory recovery, partial and substantial, which were found to be associated with differential age, degrees of chemosensory loss, and regional patterns. Uncovering the self-reported phenomenology of recovery from smell, taste, and chemesthetic disorders is the first, yet essential step, to provide healthcare professionals with the tools to take purposeful and targeted action to address chemosensory disorders and their severe discomfort.
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影响因子：
5.1
作者：
Chiesa-Estomba, C. M.;Lechien, J. R.;Saussez, S.
通讯作者：
Saussez, S.
人和小鼠大脑中 SARS-CoV-2 受体 ACE2 的空间和细胞类型分布。
影响因子：
3.4
作者：
Chen R;Wang K;Yu J;Howard D;French L;Chen Z;Wen C;Xu Z
通讯作者：
Xu Z
DOI：
10.1016/j.cmi.2021.02.008
发表时间：
2021-02-16
期刊：
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子：
--
作者：
Klein H;Asseo K;Karni N;Benjamini Y;Nir-Paz R;Muszkat M;Israel S;Niv MY
通讯作者：
Niv MY
影响因子：
64.5
作者：
Korber, Bette;Fischer, Will M.;Montefiori, David C.
通讯作者：
Montefiori, David C.
影响因子：
2.6
作者：
Landis, BN;Konnerth, CG;Hummel, T
通讯作者：
Hummel, T