Structural connectivity of cytoarchitectonically distinct human left temporal pole subregions: a diffusion MRI tractography study.
Structural connectivity of cytoarchitectonically distinct human left temporal pole subregions: a diffusion MRI tractography study.
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DOI：
10.3389/fnana.2023.1240545
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发表时间：
2023
影响因子：
2.9
通讯作者：
中科院分区：
文献类型：
--
作者：
颞极是大脑边缘皮层的主要区域之一，参与感觉知觉、情感、语义加工和社会认知等多种功能。基于细胞结构的差异，TP可以进一步细分为更小的区域（背侧，腹外侧和腹内侧），每个区域形成不同功能网络的关键节点。然而，TP亚区的脑结构连接概况尚未完全阐明。在一组31名健康受试者中使用扩散MRI数据，我们的目的是阐明三个细胞结构不同的TP亚区的全面结构连接。扩散张量成像（DTI）分析表明，主要的联合纤维通路，如下纵，中纵，弓状和钩束提供结构连接的TP。进一步的分析表明，部分重叠，但仍然不同的结构连接模式在TP次区域。具体而言，背侧亚区与顶叶中的广泛区域密切相关，腹外侧亚区与包括默认语义网络成分的区域密切相关，腹内侧亚区与边缘系统和边缘系统区域密切相关。我们的研究结果表明，参与的TP在一组广泛的，但不同的网络皮层区域，符合其功能的作用。
The temporal pole (TP) is considered one of the major paralimbic cortical regions, and is involved in a variety of functions such as sensory perception, emotion, semantic processing, and social cognition. Based on differences in cytoarchitecture, the TP can be further subdivided into smaller regions (dorsal, ventrolateral and ventromedial), each forming key nodes of distinct functional networks. However, the brain structural connectivity profile of TP subregions is not fully clarified. Using diffusion MRI data in a set of 31 healthy subjects, we aimed to elucidate the comprehensive structural connectivity of three cytoarchitectonically distinct TP subregions. Diffusion tensor imaging (DTI) analysis suggested that major association fiber pathways such as the inferior longitudinal, middle longitudinal, arcuate, and uncinate fasciculi provide structural connectivity to the TP. Further analysis suggested partially overlapping yet still distinct structural connectivity patterns across the TP subregions. Specifically, the dorsal subregion is strongly connected with wide areas in the parietal lobe, the ventrolateral subregion with areas including constituents of the default-semantic network, and the ventromedial subregion with limbic and paralimbic areas. Our results suggest the involvement of the TP in a set of extensive but distinct networks of cortical regions, consistent with its functional roles.
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DOI：
10.1093/cercor/bhp289
发表时间：
2010-09
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Blaizot X;Mansilla F;Insausti AM;Constans JM;Salinas-Alamán A;Pró-Sistiaga P;Mohedano-Moriano A;Insausti R
通讯作者：
Insausti R
影响因子：
14.5
作者：
Acosta-Cabronero, Julio;Patterson, Karalyn;Nestor, Peter J.
通讯作者：
Nestor, Peter J.
影响因子：
5.3
作者：
Croxson, PL;Johansen-Berg, H;Rushworth, MFS
通讯作者：
Rushworth, MFS
使用扩散张量成像对人类颞极进行基于连通性的分割
影响因子：
3.7
作者：
Fan, Lingzhong;Wang, Jiaojian;Jiang, Tianzi
通讯作者：
Jiang, Tianzi
影响因子：
2.3
作者：
Fernandez-Jaen, Alberto;Lopez-Martin, Sara;Calleja-Perez, Beatriz
通讯作者：
Calleja-Perez, Beatriz