Viral infections in immunocompromised patients.
Viral infections in immunocompromised patients.
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DOI：
10.1016/j.bbmt.2010.11.008
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发表时间：
2011-01
影响因子：
4.3
通讯作者：
Ljungman, Per
中科院分区：
文献类型：
--
作者：
Englund, Janet;Feuchtinger, Tobias;Ljungman, Per
病毒在普通人群中引起急性呼吸道疾病，并导致所有年龄、有基本医疗条件的人住院，也是移植受者呼吸系统疾病的常见原因。随着敏感和可靠的分子检测方法的广泛应用，在世界各地的移植受者中都检测到了常见的呼吸道病毒，包括呼吸道合胞病毒(RSV)、流感和副流感病毒(PIV)、腺病毒、鼻病毒(RhV)和冠状病毒(CoronaVirus)。最近，在有症状的移植受者中也发现了新发现的病毒，如人类偏肺病毒(HMPV)[1，2]、新的冠状病毒株[3]和博卡病毒[4]。社区获得性呼吸道病毒(CRV)对移植受者的发病率和死亡率有重大影响，导致各种疾病，从自限性上呼吸道疾病(URI)到危及生命的下呼吸道感染(LRTI)，有时还会引起播散性疾病。疾病的表现取决于特定的病毒、移植的类型以及免疫缺陷的类型、程度和持续时间。感染这些病毒后的肺炎可能主要是病毒、细菌、真菌或混合来源。一些人
Viruses that cause acute respiratory illness in the general population and are responsible for hospitalizations in persons of all ages with underlying medical conditions are also a common cause of respiratory disease in transplant recipients. With the widespread availability of sensitive and reliable molecular detection methods, common respiratory viruses including respiratory syncytial virus (RSV), influenza and parainfluenza viruses (PIVs), adenoviruses, rhinoviruses (RhV), and coronaviruses have been detected worldwide in transplant recipients. More recently, newly identified viruses such as human metapneumoviruses (HMPV)[1, 2], new strains of coronaviruses [3], and bocavirus have also been detected in symptomatic transplant recipients [4].Community-acquired respiratory viruses (CRV) have a significant impact on the morbidity and mortality of the transplant recipient, causing a variety of diseases ranging from self-limited upper respiratory tract illnesses (URIs) to life-threatening lower respiratory tract infection (LRTI) and occasionally disseminated disease. Disease manifestations are dependent on the specific virus, the type of transplant, and the type, degree, and duration of immune deficiency. Pneumonia following infection with these viruses may be primarily viral, bacterial, fungal, or mixed in origin. Some
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影响因子：
6.4
作者：
Boivin, G;Abed, Y;Anderson, LJ
通讯作者：
Anderson, LJ
影响因子：
11.8
作者：
Pauksen, K;Linde, A;Ljungman, P
通讯作者：
Ljungman, P
影响因子：
6.5
作者：
Ljungman, P;Nahi, H;Linde, A
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影响因子：
120.7
作者：
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MCCARTHY, CA
影响因子：
20.3
作者：
Machado, CM;Gonçalves, FB;de Souza, VAUF
通讯作者：
de Souza, VAUF