Comparing evolvement of visual field defect in neuromyelitis optica spectrum disorder-optic neuritis and idiopathic optic neuritis: a prospective study.
Comparing evolvement of visual field defect in neuromyelitis optica spectrum disorder-optic neuritis and idiopathic optic neuritis: a prospective study.
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比较视神经脊髓炎谱系障碍-视神经炎和特发性视神经炎视野缺损的演变：一项前瞻性研究
DOI：
10.1186/s12886-022-02510-y
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发表时间：
2022-08-09
影响因子：
2
通讯作者：
Yang, Hui
中科院分区：
文献类型：
--
作者：
Liang, Jiaqi;Zhang, Yuxin;Liu, Kaiqun;Xu, Xiaoyu;Zhao, Xiujuan;Qiu, Wei;Zhang, Xinyu;Yang, Hui
关键词：
To compare the evolvement of visual field (VF) defect in neuromyelitis optica spectrum disorder-optic neuritis (NMOSD-ON) and idiopathic optic neuritis (IDON). This prospective study involved 104 optic neuritis (ON) patients followed up for ≥ 6 months (33 patients with NMOSD-ON and 71 patients with IDON). The pattern and recovery pattern of VF defect, mean defect (MD) and pattern standard deviation (PSD) of VF, as well as BCVA at onset, 1 month (1 m), 3 months (3 m), and ≥ 6 months (6 m) after onset were compared between two groups. Analysis of these indicators in first episode patients was also done. Diffuse abnormalities and nerve fiber bundle abnormalities were the two most common patterns in both groups. The percentage of neurologic abnormality of VF defect in NMOSD-ON was higher than that of IDON. Compared with the IDON group, the MD and PSD of NMOSD-ON group were significantly worse at each follow-up. While a positive correlation in BCVA was found between 1 m and ≥ 6 m in the NMOSD-ON group only, a positive correlation was found between 1 m and ≥ 6 m in MD and PSD of both groups. A positive correlation was found between 3 m and ≥ 6 m in MD, PSD and BCVA of both groups. The quadrant recovery pattern was the most common pattern in both groups (57.1% in NMOSD-ON and 57.4% in IDON). The analysis of the first episode subgroup further confirmed the observation above. The NMOSD-ON patients tended to suffer more severe VF damage, VF irregularity and worse prognosis than that of IDON patients. Diffuse abnormalities and nerve fiber bundle abnormalities were the two most common types in both groups, while neurologic abnormality more common in NMOSD-ON and central scotoma more common in IDON. The visual functions of 1 m in NMOSD-ON and 3 m in IDON were related to its prognosis.
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影响因子：
--
作者：
Keltner, John L.;Johnson, Chris A.;Cello, Kimberly E.;Dontchev, Mariya;Gal, Robin L.;Beck, Roy W.
通讯作者：
Beck, Roy W.
影响因子：
2.6
作者：
Nakajima H;Hosokawa T;Sugino M;Kimura F;Sugasawa J;Hanafusa T;Takahashi T
通讯作者：
Takahashi T
影响因子：
9.9
作者：
Wingerchuk DM;Banwell B;Bennett JL;Cabre P;Carroll W;Chitnis T;de Seze J;Fujihara K;Greenberg B;Jacob A;Jarius S;Lana-Peixoto M;Levy M;Simon JH;Tenembaum S;Traboulsee AL;Waters P;Wellik KE;Weinshenker BG;International Panel for NMO Diagnosis
通讯作者：
International Panel for NMO Diagnosis
DOI：
10.1177/1352458514567216
发表时间：
2015-05
期刊：
Multiple sclerosis (Houndmills, Basingstoke, England)
影响因子：
--
作者：
Bennett JL;de Seze J;Lana-Peixoto M;Palace J;Waldman A;Schippling S;Tenembaum S;Banwell B;Greenberg B;Levy M;Fujihara K;Chan KH;Kim HJ;Asgari N;Sato DK;Saiz A;Wuerfel J;Zimmermann H;Green A;Villoslada P;Paul F;GJCF-ICC&BR
通讯作者：
GJCF-ICC&BR
影响因子：
--
作者：
KELTNER, JL;JOHNSON, CA;BECK, RW
通讯作者：
BECK, RW