Cardiorespiratory health effects of gaseous ambient air pollution exposure in low and middle income countries: a systematic review and meta-analysis.

Cardiorespiratory health effects of gaseous ambient air pollution exposure in low and middle income countries: a systematic review and meta-analysis.
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DOI:
10.1186/s12940-018-0380-3
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发表时间:
2018-04-18
期刊:
Environmental health : a global access science source
影响因子:
--
通讯作者:
Kurmi O
Kurmi O
中科院分区:
其他
文献类型:
--
作者:
Newell K;Kartsonaki C;Lam KBH;Kurmi O

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由于缺乏对低收入和中等收入国家(LMIC)周围环境中气态污染物(氮氧化物[NOx]、二氧化硫[SO2]、一氧化碳[CO]和臭氧[O3])对健康结果影响的研究,导致依赖高收入国家(HIC)的研究结果。本系统性综述和荟萃分析专门研究了中低收入国家气态污染物对心肺健康的影响。进行了系统搜索,并按污染物、滞后和结果汇总了估计值,并以每增加10 μg/m3(NOx、SO2、O3)或1 ppm(CO)污染物的超额相对风险表示。进行分组分析,检查估计的具体成果,城市和共同污染物的调整。60项研究符合纳入标准,大多数(44项)来自东亚和太平洋地区。同一天NOx增加10 μg/m3分别与心血管和呼吸系统死亡率增加0.92%(95%CI:0.44,1.39)和0.70%(0.01,1.40)相关,同一天NOx与发病率无关。同一天,二氧化硫分别导致呼吸道发病率和心血管死亡率增加0.73%(0.04,1.42)和0.50%(0.01,1.00)。急性暴露于气态环境空气污染(AAP)与中低收入国家发病率和死亡率的增加有关,观察到与心肺死亡率的最大关联。本文的在线版本(10.1186/s12940-018-0380-3)包含补充材料,可供授权用户使用。
Lack of research on the effects of gaseous pollutants (nitrogen oxides [NOx], sulfur dioxide [SO2], carbon monoxide [CO] and ozone [O3]) in the ambient environment on health outcomes from within low and middle income countries (LMICs) is leading to reliance on results from studies performed within high income countries (HICs). This systematic review and meta-analysis examines the cardiorespiratory health effects of gaseous pollutants in LMICs exclusively. Systematic searching was carried out and estimates pooled by pollutant, lag and outcome, and presented as excess relative risk per 10 μg/m3 (NOx, SO2, O3) or 1 ppm (CO) increase pollutant. Sub-group analysis was performed examining estimates by specific outcomes, city and co-pollutant adjustment. Sixty studies met the inclusion criteria, most (44) from the East Asia and Pacific region. A 10 μg/m3 increase in same day NOx was associated with 0.92% (95% CI: 0.44, 1.39), and 0.70% (0.01, 1.40) increases in cardiovascular and respiratory mortality respectively, same day NOx was not associated with morbidity. Same day sulfur dioxide was associated with 0.73% (0.04, 1.42) and 0.50% (0.01, 1.00) increases in respiratory morbidity and in cardiovascular mortality respectively. Acute exposure to gaseous ambient air pollution (AAP) is associated with increases in morbidity and mortality in LMICs, with greatest associations observed for cardiorespiratory mortality. The online version of this article (10.1186/s12940-018-0380-3) contains supplementary material, which is available to authorized users.
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