MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma.
MRI before biopsy correlates with depth of invasion corrected for shrinkage rate of the histopathological specimen in tongue carcinoma.
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DOI：
10.1038/s41598-021-00398-0
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发表时间：
2021-10-25
影响因子：
4.6
通讯作者：
Ikeda T
中科院分区：
文献类型：
--
作者：
Harada H;Tomioka H;Hirai H;Kuroshima T;Oikawa Y;Nojima H;Sakamoto J;Kurabayashi T;Kayamori K;Ikeda T
本研究的目的是评估哪种放射学浸润深度（r-DOI）测量与临床DOI（c-DOI）最一致，该临床DOI（c-DOI）来自对组织病理学标本收缩率的校正。我们回顾性分析了2006年至2019年期间接受舌切除术的128例舌癌患者。首先，评估福尔马林固定和组织病理学标本制备过程中的宽度收缩率。根据收缩率，开发了从病理DOI（p-DOI）计算c-DOI的公式。评价c-DOI和r-DOI之间的相关性。组织病理学标本制备过程中的标本收缩率为10.3%。在此基础上，我们得出了基于p-DOI和制备收缩率的c-DOI的正确公式：c-DOI = p-DOI × 100/89.7。通过超声（n = 128）、活检前MRI（n = 18）和活检后MRI（n = 110）测量的c-DOI与r-DOI的相关性回归方程分别为y = 1.12 * x + 0.21、y = 0.89 * x-0.26和y = 0.52 * x + 2.63，决定系数分别为0.664、0.891和0.422。总之，活检前使用MRI的r-DOI与c-DOI最强相关。
The purpose of this study was to evaluate which radiological depth of invasion (r-DOI) measurement is the most concordant to clinical DOI (c-DOI) derived from correction for the shrinkage rate of the histopathological specimens. We retrospectively reviewed 128 patients with tongue carcinoma who had undergone glossectomy between 2006 and 2019. At first, the width shrinkage rate during formalin fixation and preparation process of histopathological specimens was evaluated. From the shrinking rates, a formula to calculate c-DOI from pathological DOI (p-DOI) was developed. The correlation between c-DOI and r-DOI was evaluated. The specimen shrinkage rate during the histopathological specimen preparation process was 10.3%. Based on that, we yielded the correct formula for c-DOI based on p-DOI and preparation shrinkage rate: c-DOI = p-DOI × 100/89.7. The regression equations for the association of c-DOI with r-DOI measured by ultrasound (n = 128), MRI before biopsy (n = 18), and MRI after biopsy (n = 110) were y = 1.12 * x + 0.21, y = 0.89 * x − 0.26, and y = 0.52 * x + 2.63, respectively, while the coefficients of determination were 0.664, 0.891, and 0.422, respectively. In conclusion, r-DOI using MRI before biopsy most strongly correlated with c-DOI.
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DOI：
10.1016/j.ijom.2013.12.009
发表时间：
2014-07-01
影响因子：
2.4
作者：
Yesuratnam, A.;Wiesenfeld, D.;Phal, P. M.
通讯作者：
Phal, P. M.
DOI：
10.1016/j.ijom.2009.01.004
发表时间：
2009-06-01
影响因子：
2.4
作者：
Jung, J.;Cho, N. H.;Kim, S. -H
通讯作者：
Kim, S. -H
影响因子：
3.5
作者：
Yoon, B. C.;Bulbul, M. D.;Juliano, A. F.
通讯作者：
Juliano, A. F.
DOI：
10.1186/s40463-016-0172-0
发表时间：
2016-11-22
期刊：
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
影响因子：
--
作者：
Alsaffar HA;Goldstein DP;King EV;de Almeida JR;Brown DH;Gilbert RW;Gullane PJ;Espin-Garcia O;Xu W;Irish JC
通讯作者：
Irish JC
影响因子：
2.2
作者：
Baba, Akira;Ojiri, Hiroya;Goto, Tazuko K.
通讯作者：
Goto, Tazuko K.