Getting heavier, younger: trajectories of obesity over the life course.
Getting heavier, younger: trajectories of obesity over the life course.
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DOI：
10.1038/ijo.2009.235
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发表时间：
2010-04
影响因子：
4.9
通讯作者：
Gurney, J. G.
中科院分区：
文献类型：
--
作者：
Lee, J. M.;Pilli, S.;Gebremariam, A.;Keirns, C. C.;Davis, M. M.;Vijan, S.;Freed, G. L.;Herman, W. H.;Gurney, J. G.
尽管最近肥胖的趋势已经有了很好的记录，但出生队列中从儿童早期到成年的肥胖代际模式并没有得到很好的描述，这是最近儿童肥胖症流行的原因。这种趋势可能会对包括2型糖尿病在内的人群亚群中肥胖相关疾病的流行产生影响。我们的目标是评估美国人口在整个生命过程中肥胖的轨迹，并按性别和种族进行评估。我们对参加国家健康和营养检查调查(1971-2006)的美国人进行了肥胖的年龄、时期和出生队列分析。肥胖定义为体重指数≥95百分位数(2-16岁)或≥30 kg/m2(16岁以上)。年龄由个人在每次NHANES调查中的年龄表示，周期由每次调查的年中点定义，队列通过从周期中减去年龄来计算。最近出生的人群在特定年龄段变得肥胖的比例更大，并且在他们的一生中经历了更长时间的肥胖。例如，虽然1966-75年和1976-85年出生队列的肥胖率估计在20-29岁时至少达到20%，但1946-55年和1956-65年出生队列只在30-39岁时达到这一水平，1936-45年出生队列达到40-49岁，1926-35年出生队列达到50-59岁。与男性相比，女性的趋势尤其明显，与白人群体相比，黑人的趋势尤为明显。在最近出生的队列中，不断累积的超重暴露可能会对美国人口中未来的2型糖尿病发病率和死亡率产生深远的影响。
Although recent trends in obesity have been well documented, generational patterns of obesity from early childhood through adulthood across birth cohorts, which account for the recent epidemic of childhood obesity, have not been well described. Such trends may have implications for the prevalence of obesity-associated conditions among population subgroups, including type 2 diabetes. Our objective was to evaluate trajectories of obesity over the life course for the US population, overall and by gender and race. We conducted an age, period, and birth cohort analysis of obesity for US individuals who participated in the National Health and Nutrition Examination Surveys (1971-2006). Obesity was defined as a body mass index ≥ 95th percentile for individuals aged 2-16 years or ≥ 30 kg/m2 among individuals older than 16 years. Age was represented by the age of the individual at each NHANES survey, period was defined by the year midpoint of each survey, and cohort was calculated by subtracting age from period. Recent birth cohorts are becoming obese in greater proportions for a given age, and are experiencing a greater duration of obesity over their lifetime. For example, whereas the 1966-75 and 1976-85 birth cohorts had reached an estimated obesity prevalence of at least 20% by 20-29 years of age, this level was only reached by 30-39 years for the 1946-55 and 1956-65 birth cohorts, by 40-49 years for the 1936-45 birth cohort, and by 50-59 years of age for the 1926-35 birth cohort. Trends are particularly pronounced for female compared with male, and black compared with white cohorts. The increasing cumulative exposure to excess weight over the lifetime of recent birth cohorts will likely have profound implications for future rates of type 2 diabetes, and mortality within the US population.
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影响因子：
120.7
作者：
Flegal, KM;Carroll, MD;Johnson, CL
通讯作者：
Johnson, CL
影响因子：
--
作者：
Brancati, FL;Wang, NY;Klag, MJ
通讯作者：
Klag, MJ
影响因子：
120.7
作者：
Narayan, KMV;Boyle, JP;Williamson, DF
通讯作者：
Williamson, DF
影响因子：
5
作者：
Gallagher, D;Visser, M;Heymsfield, SB
通讯作者：
Heymsfield, SB
影响因子：
16.2
作者：
Cowie, Catherine C.;Engelgau, Michael M.;Gregg, Edward W.
通讯作者：
Gregg, Edward W.