Electrical features, liquid composition and toxicant emissions from 'pod-mod'-like disposable electronic cigarettes.
Electrical features, liquid composition and toxicant emissions from 'pod-mod'-like disposable electronic cigarettes.
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DOI：
10.1136/tobaccocontrol-2020-056362
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发表时间：
2022-09
期刊：
影响因子：
5.2
通讯作者：
Shihadeh A
中科院分区：
文献类型：
--
作者：
Talih S;Salman R;Soule E;El-Hage R;Karam E;Karaoghlanian N;El-Hellani A;Saliba N;Shihadeh A
调味豆荚状一次性电子烟（电子烟）的使用迅速增长，特别是在对成本敏感的年轻人和年轻人中。迄今为止，人们对它们的设计特点和有毒物质排放知之甚少。在这项研究中，我们分析了五种常用的调味一次性电子烟的电气和化学特性以及尼古丁和肺部有毒物质的排放情况，并将这些数据与JUUL的数据进行了比较，JUUL是一种基于电子烟的设备，类似于豆荚状的一次性电子烟在尺寸和形状上进行了模仿。确定了装置结构、电功率和液体组成。还测量了机器产生的气溶胶排放，包括颗粒物、尼古丁、羰基化合物和重金属。液体和气溶胶的组成进行了测量，高效液相色谱，气相色谱-质谱/火焰离子化检测，电感耦合等离子体质谱。我们发现，与JUUL不同，一次性设备没有集成微控制器来调节加热线圈的电力。建筑质量差异很大。一次性电子烟功率范围为5- 9 W，液体尼古丁浓度范围为53- 85 mg/mL（质子化形式约95%）。在15喷中，一次性用品的总尼古丁含量范围在1.6- 6.7毫克之间，总羰基化合物范围在28-138微克之间，总金属范围在1084- 5804纳克之间。JUUL的排放量接近所有这些范围的地板。一次性电子烟被设计成具有高尼古丁浓度液体，并且相对于可再充电的外观相似的电子烟，能够发射高得多的尼古丁和羰基物质。这些差异可能是由于结构质量较低，标签不可靠，以及缺乏温度控制调节，限制了操作期间的功率。从公共卫生的角度来看，规范这些设备对于限制用户暴露于羰基化合物和尼古丁非常重要，特别是因为这些设备在青少年和年轻人中很受欢迎。
Use of flavored pod-mod-like disposable electronic cigarettes (e-cigarettes) has grown rapidly, particularly among cost-sensitive youth and young adults. To date, little is known about their design characteristics and toxicant emissions. In this study, we analyzed the electrical and chemical characteristics and nicotine and pulmonary toxicant emission profiles of five commonly available flavored disposable e-cigarettes and compared these data to those of a JUUL, a cartridge-based e-cigarette device that pod-mod-like disposables emulate in size and shape. Device construction, electrical power, and liquid composition were determined. Machine-generated aerosol emissions including particulate matter, nicotine, carbonyl compounds, and heavy metals were also measured. Liquid and aerosol composition were measured by high-performance liquid chromatography, gas chromatography-mass spectrometry/flame ionization detection, and inductively coupled plasma mass spectrometry. We found that unlike JUUL, disposable devices did not incorporate a microcontroller to regulate electrical power to the heating coil. Quality of construction varied widely. Disposable e-cigarette power ranged between 5–9W and liquid nicotine concentration ranged between 53–85mg/mL (~95% in the protonated form). In 15 puffs, total nicotine yield for the disposables ranged between 1.6–6.7mg, total carbonyls ranged between 28–138µg, and total metals ranged between 1084–5804ng. JUUL emissions were near the floors of all of these ranges. Disposable e-cigarettes are designed with high nicotine concentration liquids and are capable of emitting much higher nicotine and carbonyl species relative to rechargeable look-alike e-cigarettes. These differences are likely due to the lower quality in construction, unreliable labeling, and lack of temperature control regulation that limits the power during operation. From a public health perspective, regulating these devices is important to limit user exposure to carbonyls and nicotine, particularly because these devices are popular with youth and young adults.
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DOI：
10.3390/ijerph17082767
发表时间：
2020-04-01
影响因子：
--
作者：
Son, Yeongkwon;Bhattarai, Chiranjivi;Khlystov, Andrey
通讯作者：
Khlystov, Andrey
影响因子：
33.9
作者：
Gentzke, Andrea S.;Creamer, MeLisa;King, Brian A.
通讯作者：
King, Brian A.
DOI：
10.1056/nejmsa1607538
发表时间：
2017-01-26
期刊：
The New England journal of medicine
影响因子：
--
作者：
Kasza KA;Ambrose BK;Conway KP;Borek N;Taylor K;Goniewicz ML;Cummings KM;Sharma E;Pearson JL;Green VR;Kaufman AR;Bansal-Travers M;Travers MJ;Kwan J;Tworek C;Cheng YC;Yang L;Pharris-Ciurej N;van Bemmel DM;Backinger CL;Compton WM;Hyland AJ
通讯作者：
Hyland AJ
影响因子：
6.1
作者：
Mallock, Nadja;Trieu, Hai Linh;Luch, Andreas
通讯作者：
Luch, Andreas
影响因子：
4.7
作者：
Talih, Soha;Balhas, Zainab;Shihadeh, Alan
通讯作者：
Shihadeh, Alan