Determinants of pre-eclampsia/Eclampsia among women attending delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: a case control study.
Determinants of pre-eclampsia/Eclampsia among women attending delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: a case control study.
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DOI：
10.1186/s12884-017-1507-1
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发表时间：
2017-09-15
影响因子：
3.1
通讯作者：
Tsegay L
中科院分区：
文献类型：
--
作者：
Grum T;Seifu A;Abay M;Angesom T;Tsegay L
先兆子痫是一种妊娠特有的高血压疾病，通常发生在怀孕20周后。它是全世界孕产妇和围产儿发病率和死亡率的主要原因之一。在埃塞俄比亚，包括先兆子痫/子痫在内的主要直接产科并发症占产妇死亡的85%。与其他直接原因造成的死亡不同，与子痫前期/子痫相关的死亡似乎正在增加，并与多种因素有关，这使得预防这种疾病成为一项持续的挑战。这项研究的目的是评估在埃塞俄比亚亚的斯亚贝巴选定的公立医院接受分娩服务的妇女中先兆子痫/子痫的决定因素。采用以医院为基础的非匹配病例对照研究设计。这项研究于2015年12月至2016年2月在亚的斯亚贝巴两家公立医院接受分娩服务的妇女中进行，样本量为291人(97例病例和194名对照)。有先兆子痫/子痫的妇女为病例，未诊断为先兆子痫/子痫的妇女为对照组。采用病例对照、发病密度抽样和访谈者问卷调查的方法。将数据输入Epi Info 7软件，并输出到Stata 14进行清理和分析。描述性统计用于以病例和对照之间的比较表显示数据。采用卡方检验比较病例与对照的分类变量。计算双变量和多变量Logistic回归分析以确定先兆子痫/子痫的决定因素。与子痫前期或子痫有统计学意义的相关因素有：初孕(AOR：2.68，95%CI：1.38，5.22)、孕期先兆子痫病史(AOR：4.28，95%CI：1.61，11.43)、多胎妊娠(AOR：8.22，95%CI：2.97，22.78)、孕期接受营养咨询(AOR：0.22，95%CI：0.1，0.48)和孕期饮酒(AOR：3.97，95%CI：1.8，8.75)。这项研究确定了先兆子痫/子痫的保护性因素和危险因素。为了及时诊断和治疗先兆子痫，卫生工作者应该特别关注初孕和多胎妊娠的妇女。此外，卫生保健提供者应在ANC期间提供营养咨询，包括避免在怀孕期间饮酒。本文的在线版本(10.1186/s12884-0171507-1)包含向授权用户提供的补充材料。
Pre-eclampsia is a pregnancy-specific hypertensive disorder usually occurs after 20 weeks of gestation. It is one of the leading causes of maternal and perinatal morbidity and mortality worldwide. In Ethiopia, the major direct obstetric complications including pre-eclampsia/eclampsia account for 85% of the maternal deaths. Unlike deaths due to other direct causes, pre-eclampsia/ eclampsia related deaths appear to be increasing and linked to multiple factors, making prevention of the disease a continuous challenge. The aim of this study is to assess determinants of pre-eclampsia/eclampsiaamong women attending delivery services in selected public hospitals in Addis Ababa, Ethiopia. Hospital based unmatched case control study design was employed. The study wasconducted in Addis Ababa among women attending delivery services in two public hospitals from December, 2015 G.C. to February, 2016 G.C. with sample size of 291 (97 cases and 194 controls). Women with pre-eclampsia/eclampsia were cases and women who had not diagnosed for pre-eclampsia/eclampsia were controls. Case-control incidence density sampling followed by interviewer administered was conducted using pretested questionnaire. The data was entered in Epi Info 7 software and exported to STATA 14 for cleaning and analysis. Descriptive statistics were used todisplay the data using tables compared between cases and controls. To compare categorical variables between cases and controls Chi-squared testwas used. Both bivariable and multivariable logistic regression analyses were computed to identify the determinants of pre-eclampsia/eclampsia. Factors that were found to have statistically significant association with pre-eclampsia or eclampsia were primigravida (AOR: 2.68, 95% CI: 1.38, 5.22), history of preeclampsia on prior pregnancy (AOR: 4.28, 95% CI: 1.61, 11.43), multiple pregnancy (AOR: 8.22, 95% CI: 2.97, 22.78), receiving nutritional counseling during pregnancy (AOR: 0.22, 95% CI: 0.1, 0.48) and drinking alcohol during pregnancy (AOR: 3.97, 95% CI: 1.8, 8.75). The study identified protective and risk factors for pre-eclampsia/eclampsia. To promptly diagnose and treat pre-eclampsia, health workers should give special attention to women with primigravida and multiple pregnancy. Besides, health care providers should provide nutritional counseling during ANC, including avoiding drinking alcohol during their pregnancy. The online version of this article (10.1186/s12884-017-1507-1) contains supplementary material, which is available to authorized users.
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DOI：
10.4021/jocmr1682w
发表时间：
2014-02
期刊：
Journal of clinical medicine research
影响因子：
--
作者：
Al-Jameil N;Aziz Khan F;Fareed Khan M;Tabassum H
通讯作者：
Tabassum H
影响因子：
3.1
作者：
Tessema, Gizachew Assefa;Tekeste, Abebe;Ayele, Tadesse Awoke
通讯作者：
Ayele, Tadesse Awoke
影响因子：
3.3
作者：
Kiondo, Paul;Wamuyu-Maina, Gakenia;Okong, Pius
通讯作者：
Okong, Pius
DOI：
10.2147/ijwh.s47056
发表时间：
2013
期刊：
International journal of women's health
影响因子：
--
作者：
Guerrier G;Oluyide B;Keramarou M;Grais RF
通讯作者：
Grais RF
影响因子：
7.2
作者：
Roberts, James M.;August, Phyllis A.;Ngaiza, Karina
通讯作者：
Ngaiza, Karina