Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China.
Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China.
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亚健康：定义、诊断标准和中国中部地区的潜在患病率
DOI：
10.1186/1471-2458-13-446
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发表时间：
2013-05-04
影响因子：
4.5
通讯作者：
Xie Q
中科院分区：
文献类型：
--
作者：
Li G;Xie F;Yan S;Hu X;Jin B;Wang J;Wu J;Yin D;Xie Q
研究背景全面评估健康状况是有效实施公共卫生干预措施的必要条件。然而，条款，以解决健康和疾病之间的中间状态是缺乏的，导致公众忽视这种状态，从而增加发展diseases.MethodsA横断面健康调查的1,473名随机招募的中国汉族成年人的性别生活在中国中部地区的风险。亚健康的诊断标准为：体重指数≥ 25 kg/m2或腰围男性≥ 102 cm，女性≥ 88 cm;收缩压120-139 mmHg和/或舒张压80-89 mmHg;血清甘油三酯水平≥ 150 mg/dL和/或总胆固醇水平≥ 200 mg/dL和/或男性高密度脂蛋白胆固醇水平< 40 mg/dL和女性<50 mg/dL;血清葡萄糖水平110-125 mg/dL;估计肾小球滤过率60-89 ml/min/1.73 m2;肝功能检查中肝酶水平在41-59 U/L之间，或患有脂肪肝但受影响肝细胞< 33%;氧化应激生物标志物水平超出95%的参考范围;结果中部地区亚健康和疾病的患病率分别为36.6%和43.1%，分别。疾病患病率从20-39岁参与者的26.3%增加到40-59岁和60岁或以上参与者的47.6%和78.9%。与20-39岁的参与者相比，60岁及以上参与者的健康和亚健康患病率分别下降了86.7%和60.3%。亚健康的患病率增加与生活方式风险评分的增加，而健康和疾病的患病率均reduced.ConclusionThe亚健康和疾病的患病率是在中国中部地区高。亚健康与高生活方式风险评分相关。无论是卫生保健部门还是公众都应该更加关注亚健康。生活方式的改变和/或心理干预需要改善这些条件。
BackgroundA full evaluation of health conditions is necessary for the effective implementation of public health interventions. However, terms to address the intermediate state between health and disease are lacking, leading the public to overlook this state and thus increasing the risks of developing disease.MethodsA cross-sectional health survey of 1,473 randomly recruited Chinese Han adults of both sexes living in the central region of China. The criteria for diagnosis of subhealth was defined as the presence of ≥ 1 of the following abnormalities: body mass index ≥ 25 kg/m2or waist circumference ≥ 102 cm in men and 88 cm in women; systolic pressure 120–139 mmHg and/or diastolic pressure 80–89 mmHg; serum triglyceride level ≥ 150 mg/dL and/or total cholesterol level ≥ 200 mg/dL and/or high-density lipoprotein cholesterol level < 40 mg/dL in men and 50 mg/dL in women; serum glucose level 110–125 mg/dL; estimated glomerular filtration rate 60–89 ml/min/1.73 m2; levels of liver enzymes in liver function tests between 41–59 U/L, or with fatty liver disease but < 33% of affected hepatocytes; levels of oxidative stress biomarkers beyond the reference range of 95%; or problems with both sleep quality and psychological state.ResultsThe prevalences of subhealth and disease in the central region of China were 36.6% and 43.1%, respectively. The prevalence of disease increased from 26.3% in participants aged 20–39 years, to 47.6% and 78.9% for participants aged 40–59 years and those aged 60 years or older, respectively. Compared with participants aged 20–39, the prevalences of health and subhealth in participants aged 60 years or older decreased by 86.7% and 60.3%, respectively. The prevalence of subhealth was increased in association with increases in lifestyle risk scores, while the prevalences of both health and disease were reduced.ConclusionThe prevalences of subhealth and disease are high in central China. Subhealth is associated with high lifestyle risk scores. Both the health care sector and the public should pay more attention to subhealth. Lifestyle modifications and/or psychological interventions are needed to ameliorate these conditions.
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