Central nervous system tumors: a single center pathology review of 34,140 cases over 60 years.
Central nervous system tumors: a single center pathology review of 34,140 cases over 60 years.
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中枢神经系统肿瘤：60 年来 34,140 例单中心病理学回顾。
DOI：
10.1186/1472-6890-13-14
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发表时间：
2013-05-02
影响因子：
--
通讯作者：
Zhou L
中科院分区：
文献类型：
--
作者：
Chen L;Zou X;Wang Y;Mao Y;Zhou L
肿瘤流行病学是中枢神经系统肿瘤研究的重要组成部分。重新评估原始切片可以更新我们对肿瘤谱的认识。在这里，我们讨论的特点，中枢神经系统肿瘤病理在一个单一的中心。收集1950 - 2009年共34140例病例，其中1990 - 2009年的切片按WHO 2007分类法重新评估，1950 - 1989年的病例按既往病理诊断进行分类。1990年至2009年期间的7种CNS肿瘤分类如下：神经上皮组织脑膜肿瘤占38.0%鞍区肿瘤占36.5%（4.1%），生殖细胞肿瘤（1.3%），颅神经和椎旁神经肿瘤淋巴瘤和造血系统肿瘤（1.7%），转移瘤（5.1%）。总体而言，男性在大多数CNS肿瘤亚型的分布中超过女性，而脑膜肿瘤更常见于女性。淋巴瘤和造血系统肿瘤的病例数在过去五年中增长最快，神经上皮肿瘤的分布在过去二十年中保持稳定。尽管存在交叉样本偏倚的可能性，但该系列的数据可能表明与其他发展中国家可能发生的CNS肿瘤谱相似。
Tumor epidemiology is a significant part of CNS (central nervous system) tumor studies. Reassessment of original sections can update our knowledge of tumor spectrum. Here, we discuss the features of CNS tumor pathology in a single center. A total of 34140 cases from 1950 to 2009 were collected; sections from 1990 to 2009 were reassessed according to WHO 2007 classification, and cases from 1950 to 1989 were classified according to the previous pathological diagnosis. Seven CNS tumor categories during 1990 to 2009 were as follow: neuroepithelial tissue (38.0%), tumors of the meninges (36.5%), tumors of the sellar region (4.1%), germ cell tumors (1.3%), tumors of cranial and paraspinal nerves (13.3%), lymphomas and hematopoietic neoplasm (1.7%), metastatic tumors (5.1%), where histological types by age and sex were diverse. Overall, males exceeded females in distributions of most CNS tumor subtypes, while tumors of the meninges occurred more frequently in females. The case number of lymphomas and hematopoietic neoplasms grew the fastest during the past five years, and the distribution of neuroepithelial tumors remained stable over the past twenty years. Despite the possibilities of cross sample biases, the data in this series could suggest a similar CNS tumor spectrum as might occur in other developing countries.
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影响因子：
1.4
作者：
Makino, Keishi;Nakamura, Hideo;Kuratsu, Jun-ichi
通讯作者：
Kuratsu, Jun-ichi
影响因子：
3.9
作者：
Bauchet, Luc;Rigau, Valerie;Dhellemmes, Patrick
通讯作者：
Dhellemmes, Patrick
影响因子：
4.8
作者：
Rousseau, Audrey;Mokhtari, Karima;Duyckaerts, Charles
通讯作者：
Duyckaerts, Charles
DOI：
10.1093/jnci/djp415
发表时间：
2009-12-16
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
Deltour, Isabelle;Johansen, Christoffer;Schuz, Joachim
通讯作者：
Schuz, Joachim
影响因子：
3.3
作者：
Nakamura, Hideo;Makino, Keishi;Kuratsu, Jun-ichi
通讯作者：
Kuratsu, Jun-ichi