Photosensitivity in cutaneous lupus erythematosus.
Photosensitivity in cutaneous lupus erythematosus.
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DOI:
10.1111/phpp.12018
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发表时间:
2013-02
期刊:
影响因子:
--
通讯作者:
Chong BF
中科院分区:
文献类型:
--
作者:
Kim A;Chong BF
Cutaneous lupus erythematosus (CLE) encompasses several different forms including acute, subacute, and chronic manifestations that may or may not occur in the setting of systemic lupus erythematosus (SLE). Ultraviolet radiation (UVR) is a well-known exacerbating factor for CLE, with photosensitivity comprising one of the American College of Rheumatology (ACR) diagnostic criteria for SLE. However, discerning true photosensitivity in this population is difficult due to the broad language utilized by the ACR and the delayed-onset nature of photosensitive lupus lesions. Photoprovocation testing provides a more objective method to measure photosensitivity, but photoprovocation trials demonstrate significantly varying results due to protocol variations. Despite UVR’s deleterious effect on lupus patients, UVA-1 may have therapeutic benefits as shown by some observations on murine and human lupus subjects. Accurately discerning photosensitivity has diagnostic implications for SLE and provides motivation for greater patient adherence to photoprotective measures.
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DOI:
10.1084/jem.172.6.1609
发表时间:
1990-12-01
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Köck A;Schwarz T;Kirnbauer R;Urbanski A;Perry P;Ansel JC;Luger TA
通讯作者:
Luger TA
影响因子:
2.6
作者:
Cutillas-Marco E;Morales-Suárez-Varela M;Marquina-Vila A;Grant W
通讯作者:
Grant W
影响因子:
10.3
作者:
Gronhagen, C. M.;Fored, C. M.;Nyberg, F.
通讯作者:
Nyberg, F.
影响因子:
3.4
作者:
Jabara, Benjamin;Dahlgren, Mollie;McGrath, Hugh, Jr.
通讯作者:
McGrath, Hugh, Jr.
影响因子:
3.3
作者:
FUCHS, J;HUFLEJT, ME;PACKER, L
通讯作者:
PACKER, L