Differences in number and distribution of striatal calbindin medium spiny neurons between a vocal-learner (Melopsittacus undulatus) and a non-vocal learner bird (Colinus virginianus).
Differences in number and distribution of striatal calbindin medium spiny neurons between a vocal-learner (Melopsittacus undulatus) and a non-vocal learner bird (Colinus virginianus).
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DOI：
10.3389/fnana.2013.00046
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发表时间：
2013
影响因子：
2.9
通讯作者：
Martinez S
中科院分区：
文献类型：
--
作者：
Garcia-Calero E;Bahamonde O;Martinez S
纹状体突起神经元，被称为中棘神经元（msn），在哺乳动物纹状体中分为基质和纹状体两个隔间。基质结构域以钙结合蛋白免疫阳性（CB+） msn的存在为特征，而在纹状体细分中未观察到。最近在雄性斑胸草雀（一种声乐学习鸟）的两个纹状体结构中描述了类似的CB+ MSN群体的存在：纹状体囊和X区，一个与歌唱学习有关的核。雌斑胸草雀在纹状体发育过程中表现出与雄斑胸草雀相似的CB+ msn模式，但在幼年期和成虫期这些细胞丢失。本研究分析了有声学习鸟虎牙（鹦鹉目的代表）和无声学习鸟鹌鹑（鹦鹉目的代表）纹状体区域中CB+ msn的存在和分布。我们研究了CB蛋白与FoxP1的共定位，FoxP1是脊椎动物纹状体msn中表达的转录因子。我们在成年雄性和雌性虎皮猴的内侧纹状体区域观察到CB+ MSNs，尽管这种细胞类型在虎皮猴X区的潜在同源核中缺失。在鹌鹑中，我们在发育和成年阶段观察到纹状体区域的CB+细胞，但它们不与MSN标记FoxP1共定位。我们还描述了虎皮鹦鹉和鹌鹑体内CB+纹状体被膜的存在，并将这些结果与斑胸草雀幼鸟体内CB+纹状体被膜的存在进行了比较。综上所述，这些结果指出了在发声学习鸟目和非发声学习鸟目的两个代表性物种（分别是虎皮鹦鹉和鹌鹑）之间，以及在相近的发声学习鸟科之间，CB+ MSN分布的重要差异。
Striatal projecting neurons, known as medium spiny neurons (MSNs), segregate into two compartments called matrix and striosome in the mammalian striatum. The matrix domain is characterized by the presence of calbindin immunopositive (CB+) MSNs, not observed in the striosome subdivision. The existence of a similar CB+ MSN population has recently been described in two striatal structures in male zebra finch (a vocal learner bird): the striatal capsule and the Area X, a nucleus implicated in song learning. Female zebra finches show a similar pattern of CB+ MSNs than males in the developing striatum but loose these cells in juveniles and adult stages. In the present work we analyzed the existence and allocation of CB+ MSNs in the striatal domain of the vocal learner bird budgerigar (representative of psittaciformes order) and the non-vocal learner bird quail (representative of galliformes order). We studied the co-localization of CB protein with FoxP1, a transcription factor expressed in vertebrate striatal MSNs. We observed CB+ MSNs in the medial striatal domain of adult male and female budgerigars, although this cell type was missing in the potentially homologous nucleus for Area X in budgerigar. In quail, we observed CB+ cells in the striatal domain at developmental and adult stages but they did not co-localize with the MSN marker FoxP1. We also described the existence of the CB+ striatal capsule in budgerigar and quail and compared these results with the CB+ striatal capsule observed in juvenile zebra finches. Together, these results point out important differences in CB+ MSN distribution between two representative species of vocal learner and non-vocal learner avian orders (respectively the budgerigar and the quail), but also between close vocal learner bird families.
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影响因子：
1.7
作者：
ESSER, KH
通讯作者：
ESSER, KH
影响因子：
3.7
作者：
Feenders, Gesa;Liedvogel, Miriam;Rivas, Miriam;Zapka, Manuela;Horita, Haruhito;Hara, Erina;Wada, Kazuhiro;Mouritsen, Henrik;Jarvis, Erich D.
通讯作者：
Jarvis, Erich D.
影响因子：
2.9
作者：
Crittenden JR;Graybiel AM
通讯作者：
Graybiel AM
DOI：
10.1073/pnas.87.23.9445
发表时间：
1990-12-01
影响因子：
11.1
作者：
GAHR, M
通讯作者：
GAHR, M
DOI：
10.1073/pnas.82.24.8780
发表时间：
1985-12-01
影响因子：
11.1
作者：
GERFEN, CR;BAIMBRIDGE, KG;MILLER, JJ
通讯作者：
MILLER, JJ