Image analysis for retinopathy of prematurity: where are we headed?

Image analysis for retinopathy of prematurity: where are we headed?
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早产儿视网膜病变的图像分析:我们将走向何方?

DOI:
10.1016/j.jaapos.2012.08.001
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发表时间:
2012
期刊:
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
影响因子:
--
通讯作者:
Chiang,MichaelF
Chiang,MichaelF
中科院分区:
--
文献类型:
--
作者:
Chiang,MichaelF

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近几十年来,早产儿视网膜病变(ROP)的治疗取得了显著进展。临床结果改善的一个原因是,通过ROP冷冻疗法(CRYO-ROP)和ROP早期治疗(ETROP)试验,已经建立了明确的疾病识别标准。1、2这些研究表明,决定是否治疗的最关键的特征是Plus病的存在,即后极部的动脉曲折和静脉扩张大于或等于标准已发表照片的程度。1、3临床ROP诊断面临哪些挑战?视网膜血管特征,如弯曲和扩张,似乎是主观和定性的,专家之间在PLUS疾病诊断中的显著差异已在几项研究中得到证明。4-7从这个角度来看,严格的ROP研究发现,最重要的临床发现可能会在临床医生中产生最大的分歧,这是具有挑战性的。基于计算机的图像分析通过提供对视网膜血管的客观和定量测量,有可能解决这些限制。8-9《AAPOS杂志》的最新一期包括三篇论文,考察了数字图像分析在ROP Care10-12中的作用,这些论文扩展了我们对这些方法及其应用的理解。
Within several decades, remarkable progress has occurred in retinopathy of prematurity (ROP) management. One reason for improved clinical outcomes is that clear criteria for identifying disease that requires treatment have been established through the Cryotherapy for ROP (CRYO-ROP) and Early Treatment for ROP (ETROP) trials. 1, 2 These studies have shown that the most critical feature that determines whether to treat is the presence of plus disease, which is defined as arterial tortuosity and venous dilation in the posterior pole greater than or equal to that of a standard published photograph. 1, 3What are the challenges with clinical ROP diagnosis? Retinal vascular features such as tortuosity and dilation would appear to be subjective and qualitative, and significant variability in plus disease diagnosis among experts has been demonstrated in several studies. 4–7 From this perspective, it is challenging that rigorous ROP research studies have found that the most important clinical findings may produce the most disagreement among clinicians. Computer-based image analysis has potential to address these limitations by providing objective and quantitative measures of retinal vessels. 8–9 The most recent issues of the Journal of AAPOS include three papers examining the role of digital image analysis for ROP care10–12 that extend our understanding of these methods and their applications.
早产儿视网膜病变的附加疾病:血管变化的定量分析。
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