Postural sway and neurocognition in individuals meeting criteria for a clinical high-risk syndrome.

Postural sway and neurocognition in individuals meeting criteria for a clinical high-risk syndrome.
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DOI:
10.1007/s00406-021-01234-2
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发表时间:
2022-03
影响因子:
4.7
通讯作者:
Mittal VA
Mittal VA
中科院分区:
医学2区
文献类型:
--
作者:
Osborne KJ;Mittal VA

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神经认知缺陷涉及符合临床高危综合征(CHR)标准的个体。精神分裂症患者的证据表明,小脑功能障碍可能是神经认知缺陷的基础。然而,很少有研究调查在符合CHR标准的人群中是否存在类似的关联。本研究在CHR样本(N=66)中检测了matrix认知电池、体位摇摆(小脑功能指数)和SIPS-RC精神病风险评分之间的关系。较差的工作记忆和处理速度与较差的姿势控制有关。与精神分裂症的认知障碍理论一致,神经认知缺陷与这一关键人群的小脑功能障碍有关。
Neurocognitive deficits are implicated in individuals that meet criteria for a clinical high-risk (CHR) syndrome. Evidence in patients with schizophrenia suggest that cerebellar dysfunction may underlie neurocognitive deficits. However, little research has examined if similar associations are present in those meeting CHR criteria. This study examined associations between the MATRICs cognitive battery, postural sway (an index of cerebellar functioning), and SIPS-RC psychosis risk scores in a CHR sample (N=66). Poorer working memory and processing speed were associated with less postural control. Consistent with the cognitive dysmetria theory of schizophrenia, neurocognitive deficits are associated with cerebellar dysfunction in this critical population.
DOI: 10.1017/s0033291719004161
发表时间: 2021-06
影响因子: 6.9
作者:
Osborne, K. Juston;Damme, Katherine S. F.;Gupta, Tina;Dean, Derek J.;Bernard, Jessica A.;Mittal, Vijay A.
通讯作者: Mittal, Vijay A.
DOI: 10.1016/s0033-3182(95)71666-8
发表时间: 1995-05-01
期刊: PSYCHOSOMATICS
影响因子: 3.4
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通讯作者: HALL, RCW
DOI: 10.1038/s41598-019-39367-z
发表时间: 2019-02-27
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
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DOI: 10.1177/2167702614542463
发表时间: 2015-07-01
期刊: Clinical psychological science : a journal of the Association for Psychological Science
影响因子: --
作者:
Bernard JA;Mittal VA
通讯作者: Mittal VA
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发表时间: 2012-04-01
影响因子: 3.1
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